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1.发明公开ARYIiALKYL AND HETEROARYLALKYL DERIVATIVES OF CYCLOSPORINE A FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTION 有权环孢菌素A在治疗和预防病毒感染的芳基烷基和杂衍生物
公开(公告)号：EP1931696A1
公开(公告)日：2008-06-18
申请号：EP06816230.4
申请日：2006-10-02
申请人： Scynexis, Inc.
发明人： HOUCK, David, Renwick , LI, Keqiang
CPC分类号： C07K7/645
摘要： This invention provides compounds of general formula (I): (I) wherein A, B, R 1 , R2, and X are as defined in the specification, and pharmaceutical compositions prepared from the same, for use in treatment of hepatitis C virus and/or human immunodeficiency virus.
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公开(公告)号：EP2023918B1
公开(公告)日：2011-03-23
申请号：EP07795039.2
申请日：2007-05-18
申请人： Scynexis, Inc.
IPC分类号： A61K31/4025 , A61K31/4178 , A61K31/4453 , A61K31/496 , A61K31/5355 , A61K45/06 , A61K31/395 , A61P27/02
CPC分类号： A61K31/395 , A61K31/4025 , A61K31/4178 , A61K31/4453 , A61K31/496 , A61K31/5355 , A61K45/06
摘要： Provided herein are methods for treatment of ocular diseases. The methods comprise administering a compound of general Formula (I): wherein R1, R2, R3, R4 and Ak are as defined in the specification.
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3.发明公开METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF HEPATITIS C INFECTION 审中-公开方法和药物组合物用于治疗和预防丙型肝炎感染
公开(公告)号：EP1933859A2
公开(公告)日：2008-06-25
申请号：EP06816231.2
申请日：2006-10-02
申请人： Scynexis, Inc.
IPC分类号： A61K38/13
CPC分类号： A61K38/13 , A61K38/21 , A61K2300/00
摘要： This invention relates to cyclosporin derivatives of general formula (I): wherein A, B, R1, R2 and X are as defined in the specification, and pharmaceutical compositions prepared from the same, for use in treatment of hepatitis C virus.
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4.发明授权3-ETHER AND 3-THIOETHER SUBSTITUTED CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF HEPATITIS C INFECTION 有权3-醚和3-硫醚取代CICLOSPORINDERIVATE用于治疗和预防丙型肝炎感染
公开(公告)号：EP1802650B1
公开(公告)日：2011-10-26
申请号：EP05815625.8
申请日：2005-09-30
申请人： Scynexis, Inc.
摘要： This invention relates to cyclosporin derivatives of general formula (I) wherein A, B, R1,R2 and X are as defined in the specification, and pharmaceutical compositions prepared from the same, for use in treatment of hepatitis C virus.
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5.发明授权ARYLALKYL AND HETEROARYLALKYL DERIVATIVES OF CYCLOSPORINE A FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTION 有权环孢菌素A在治疗和预防病毒感染的芳基烷基和杂衍生物
公开(公告)号：EP1931696B1
公开(公告)日：2011-02-16
申请号：EP06816230.4
申请日：2006-10-02
申请人： Scynexis, Inc.
发明人： HOUCK, David, Renwick , LI, Keqiang
CPC分类号： C07K7/645
摘要： This invention provides compounds of general formula (I): (I) wherein A, B, R 1 , R2, and X are as defined in the specification, and pharmaceutical compositions prepared from the same, for use in treatment of hepatitis C virus and/or human immunodeficiency virus.
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公开(公告)号：EP2023918A2
公开(公告)日：2009-02-18
申请号：EP07795039.2
申请日：2007-05-18
申请人： Scynexis, Inc.
IPC分类号： A61K31/395 , A61P27/02
CPC分类号： A61K31/395 , A61K31/4025 , A61K31/4178 , A61K31/4453 , A61K31/496 , A61K31/5355 , A61K45/06
摘要： Provided herein are methods for treatment of ocular diseases. The methods comprise administering a compound of general Formula (I): wherein R1, R2, R3, R4 and Ak are as defined in the specification.
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7.发明公开3-ETHER AND 3-THIOETHER SUBSTITUTED CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF HEPATITIS C INFECTION 有权3-醚和3-硫醚取代CICLOSPORINDERIVATE用于治疗和预防丙型肝炎感染
公开(公告)号：EP1802650A2
公开(公告)日：2007-07-04
申请号：EP05815625.8
申请日：2005-09-30
申请人： Scynexis, Inc.
IPC分类号： C07K7/64
摘要： This invention relates to cyclosporin derivatives of general formula (I) wherein A, B, R1,R2 and X are as defined in the specification, and pharmaceutical compositions prepared from the same, for use in treatment of hepatitis C virus.
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