公开(公告)号：EP3626728A1

公开(公告)日：2020-03-25

申请号：EP18845981.2

申请日：2018-06-19

申请人： Seoul National University R & DB Foundation ,  Nibec Co., Ltd.

发明人： HAN, Seung Hyun ,  PARK, Ok-Jin ,  KIM, Jiseon ,  AHN, Ki Bum ,  PARK, Yoon Jeong ,  CHUNG, Chong-Pyoung ,  LEE, Jue-Yeon

IPC分类号： C07K7/08 ,  A23L33/18 ,  A61K38/00

摘要： The present invention relates to a peptide for inhibiting bone resorption and, more specifically, to a peptide for inhibiting bone destruction by inhibiting the differentiation and activity of osteoclasts. According to the present invention, a peptide for inhibiting bone resorption can inhibit bone destruction by inhibiting the differentiation and activity of osteoclasts, and thus can be used as a therapeutic agent for various bone diseases caused by an excessive increase in the activity of osteoclasts.

公开(公告)号：EP4344547A1

公开(公告)日：2024-04-03

申请号：EP23825351.2

申请日：2023-07-04

申请人： Seoul National University R & DB Foundation

发明人： HAN, Seung Hyun ,  PARK, Dong Hyun ,  LEE, Dongwook

IPC分类号： A01N63/20 ,  A01P3/00 ,  A61K31/70 ,  A61K35/74 ,  A61K35/744 ,  A61P31/10 ,  C09D5/14 ,  A23L33/10 ,  A23K10/16

摘要： The present invention relates to an antifungal composition using lipoteichoic acid derived from various Gram-positive bacteria to inhibit the adhesion and aggregation of Candida fungi, a pharmaceutical composition for preventing and treating candidiasis infection and the use thereof. Using this approach, since the effect of inhibiting adhesion and cohesion, which are the representative virulence factors of Candida fungal infection and candidiasis, has been confirmed, it can be used for antifungal use against Candida fungi and for prevention or treatment related to candidiasis infection.

公开(公告)号：EP3608331A1

公开(公告)日：2020-02-12

申请号：EP18780706.0

申请日：2018-03-19

申请人： Seoul National University R&DB Foundation ,  Nibec Co., Ltd.

发明人： HAN, Seung Hyun ,  KUM, Kee-Yeon ,  AHN, Ki Bum ,  PARK, Ok-Jin ,  CHUNG, Chong-Pyoung ,  PARK, Yoon Jeong ,  LEE, Jue-Yeon

IPC分类号： C07K7/08 ,  A61K8/64 ,  A61Q11/02

摘要： The present invention relates to: a composition for inhibiting biofilms, containing, as an active ingredient, a peptide derived from human β-defensin-3; and a method for inhibiting biofilms by using the composition. The peptide according to the present invention inhibits bacterial biofilms even when used alone and exhibits a remarkably increased biofilm inhibitory effect when used in combination with a conventional dental therapeutic agent, and has an effect of preventing a tooth discoloration side effect caused by a conventional dental therapeutic agent.