专利检索 ap:("Setagon, Inc.") AND inv:"OWENS, Gary K." 第 1 页

1.

发明公开
METHODS AND COMPOSITIONS FOR EXPRESSING POLYNUCLEOTIDES SPECIFICALLY IN SMOOTH MUSCLE CELLS IN VIVO 审中-公开
标题翻译： “方法和组合物多核苷酸的体内表达，特别是在平滑肌”

公开(公告)号：EP1360191A2

公开(公告)日：2003-11-12

申请号：EP02704234.0

申请日：2002-01-24

申请人： Setagon, Inc.

发明人： OWENS, Gary K. , MANABE, Ichiro

IPC分类号： C07H21/04 , A01K67/00 , C12N15/74 , C12N15/85 , C12Q1/68

CPC分类号： C12N15/85 , A01K2217/05 , A61K48/00 , C12N2830/008 , C12N2830/85 , C12N2840/44

摘要： The present invention generally relates to promoters, enhancers and other regulatory elements of smooth muscle cells ('SMC'). The invention more particularly relates to methods for the targeted knockout, or over-expression, of genes of interest within smooth muscle cells or within a subtype of smooth muscle cells. The invention further relates to methods of conferring polynucleotide expression in vivo specifically in smooth muscle cells or in subtypes of smooth muscle cells.