公开(公告)号：EP3115361A1

公开(公告)日：2017-01-11

申请号：EP15757771.9

申请日：2015-03-09

申请人： Shanghai Institute Of Materia Medica Chinese Academy of Sciences ,  Suzhou Vigonvita Life Sciences Co., Ltd. ,  Topharman Shandong Co., Ltd.

发明人： JIANG, Hualiang ,  WANG, Zhen ,  LI, Jianfeng ,  ZHANG, Rongxia ,  HE, Yang ,  LIU, Yongjian ,  BI, Minghao ,  LIU, Zheng ,  TIAN, Guanghui ,  CHEN, Weiming ,  YANG, Feipu ,  WU, Chunhui ,  WANG, Yu ,  JIANG, Xiangrui ,  YIN, Jingjing ,  WANG, Guan ,  SHEN, Jingshan

IPC分类号： C07D409/12 ,  C07D471/04 ,  C07D409/14 ,  C07D519/00 ,  C07D495/04 ,  C07D417/12 ,  C07D413/12 ,  A61K31/496 ,  A61K31/519 ,  A61K31/4709 ,  A61K31/517 ,  A61K31/538 ,  A61K31/5415 ,  A61K31/55 ,  A61P25/00 ,  A61P25/18 ,  A61P25/24 ,  A61P25/22

CPC分类号： C07D409/12 ,  C07D409/14 ,  C07D413/12 ,  C07D417/12 ,  C07D471/04 ,  C07D495/04 ,  C07D519/00

摘要： Provided are heterocyclic compounds represented by formula (I), stereoisomers or pharmaceutically acceptable salts of said compounds, a pharmaceutical composition of said compounds, and an application of said compounds in the preparation of a drug for the prevention and/or treatment of a central nervous system disease.