公开(公告)号：EP4177255A1

公开(公告)日：2023-05-10

申请号：EP21834664.1

申请日：2021-06-29

申请人： Shanghai Institute of Materia Medica, Chinese Academy of Sciences

发明人： LIU, Hong ,  WANG, Jiang ,  XIE, Cen ,  LIU, Yameng ,  HU, Shulei ,  LI, Cuina ,  GAO, Feng ,  WANG, Kanglong ,  WANG, Yong ,  ZHONG, Xianchun ,  SHI, Yuqiang ,  JIANG, Hualiang ,  CHEN, Kaixian

IPC分类号： C07D413/14 ,  C07D413/12 ,  C07D271/06 ,  A61K31/4245 ,  A61P3/00

摘要： The present invention relates to the fields of pharmaceutical chemistry and pharmacotherapeutics,and in particular to a compound as represented by general formula I, a racemate, an R-isomer, an S-isomer and a pharmaceutically acceptable salt thereof and a mixture of same, a preparation method therefor, a pharmaceutical composition containing the compound and the use thereof as an SIP receptor agonist. The oxadiazole compound involved in the present invention can be used for treating SIP receptor agonist related diseases.