专利检索 ap:("Shanghai Institute of Pharmaceutical Industry" OR "Zhejiang Hisun Pharmaceutical Co. Ltd.") AND inv:"LAI, Anping" 第 1 页

1.

发明授权
PREPARATION METHOD OF RIVASTIGMINE, ITS INTERMEDIATES AND PREPARATION METHOD OF THE INTERMEDIATES 有权
标题翻译：利福平的制备方法及其中间体和中间体的制备方法

公开(公告)号：EP2233465B1

公开(公告)日：2017-06-28

申请号：EP08700628.4

申请日：2008-01-10

申请人： Shanghai Institute of Pharmaceutical Industry , Zhejiang Hisun Pharmaceutical Co. Ltd.

发明人： ZHANG, Fuli , HU, Meng , XIE, Meihua , LAI, Anping , SUN, Rentong , CHEN, Daoxin , BAO, Rusheng , BAI, Hua

IPC分类号： C07C217/58 , C07C271/44

CPC分类号： C07C217/58 , C07B2200/07 , C07C215/50 , C07C271/44

2.

发明公开
PREPARATION METHOD OF RIVASTIGMINE, ITS INTERMEDIATES AND PREPARATION METHOD OF THE INTERMEDIATES 有权
标题翻译：用于生产利斯的明及其中间体和工艺中间体的制备方法

公开(公告)号：EP2233465A1

公开(公告)日：2010-09-29

申请号：EP08700628.4

申请日：2008-01-10

申请人： Shanghai Institute of Pharmaceutical Industry , Zhejiang Hisun Pharmaceutical Co. Ltd.

发明人： ZHANG, Fuli , HU, Meng , XIE, Meihua , LAI, Anping , SUN, Rentong , CHEN, Daoxin , BAO, Rusheng , BAI, Hua

IPC分类号： C07C211/27 , C07C69/06 , C07C271/44 , A61K31/27 , A61P25/28

CPC分类号： C07C217/58 , C07B2200/07 , C07C215/50 , C07C271/44

摘要： The present invention provides N-methylethylcarbamino-3-[(S)-1-(methyl-[(S)-1-phenylethyl] amino) ethyl] phenyl ester represented by formula (II) and its preparation method. The present invention also provides (S)-1-(3-methoxyphenyl)-N-methyl-N-[(S)-1-phenylethyl] ethylamine and 3-[(S)-1-(methyl-[(S)-1-phenylethyl] amino) ethyl] phenol as intermediates of the compound represented by formula (II), and the use of the compound represented by formula (II) for preparing rivastigmine used for treating Alzheimer disease.