公开(公告)号：EP4183774A1

公开(公告)日：2023-05-24

申请号：EP21842032.1

申请日：2021-07-16

申请人： Shanghai Senhui Medicine Co., Ltd. ,  Shanghai Shengdi Pharmaceutical Co., Ltd ,  Jiangsu Hengrui Pharmaceuticals Co., Ltd.

发明人： HUANG, Jian ,  ZHU, Lingjian ,  YU, Xiuzhao ,  SUN, Piaoyang

IPC分类号： C07C311/59 ,  A61K31/64

摘要： The present invention relates to a sulfonylurea derivative and medical uses thereof, specifically relating to the sulfonylurea derivative shown in general formula (I), a preparation method thereof, a pharmaceutical composition containing same, and a use of same for treating diseases and disorders affected by neuronal damage, for example: cerebral stroke, brain damage, neuropathic pain, migraines, inflammatory pain, chronic pain, or depression. The definition of each group in the general formula (I) is the same as that in the description.

公开(公告)号：EP4293028A1

公开(公告)日：2023-12-20

申请号：EP22752311.5

申请日：2022-02-10

申请人： Shanghai Senhui Medicine Co., Ltd. ,  Shanghai Shengdi Pharmaceutical Co., Ltd ,  Jiangsu Hengrui Pharmaceuticals Co., Ltd.

发明人： ZHU, Lingjian ,  YU, Xiuzhao ,  LIU, Xiaowu ,  BEN, Peipei ,  CHEN, Lei ,  KONG, Xianglin ,  HUANG, Jian ,  SUN, Piaoyang

IPC分类号： C07D519/00 ,  A61K31/407 ,  A61P7/02 ,  A61P9/10

摘要： The present disclosure relates to an SMTP-7 derivative and the use thereof. In particular, provided is a compound as represented by formula I or a pharmaceutically acceptable salt thereof, wherein each group is as defined in the description.