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公开(公告)号:EP4006148A1
公开(公告)日:2022-06-01
申请号:EP20847793.5
申请日:2020-07-30
申请人: Shinshu University , Kyoto Prefectural Public University Corporation , BrightPath Biotherapeutics Co., Ltd.
发明人: NAKAZAWA, Yozo , YAGYU, Shigeki , TANAKA, Miyuki , NAKAMURA, Kayoko , OKADA, Masahiro , KONDO, Makoto , SHIGEURA, Tomokuni , HIROTA, Shogo
摘要: The present disclosure includes a method of producing a cell population containing Chimeric Antigen Receptor (CAR)-expressing immune cells, comprising co-culturing CAR-expressing immune cells and cells expressing a target antigen of the CAR, wherein the CAR-expressing immune cells are cells into which a CAR gene has been introduced and the target antigen-expressing cells are normal blood cells that have been engineered to express the target antigen.