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公开(公告)号:EP2206505B1
公开(公告)日:2013-07-31
申请号:EP08790627.7
申请日:2008-06-26
申请人: Shinwa Pharmaceutical Co., Ltd. , Bio-Lab Ltd. , The Japanese Association Of Clinical Research on Supplements , Cosmo Foods Co., Ltd.
发明人: HASEGAWA, Hideo , KAN, Tatsuhiko
CPC分类号: C12N1/00 , A23K10/18 , A23L33/135 , A23V2002/00 , A23Y2220/13 , A61K8/99 , A61K35/747 , A61K2800/412 , A61Q19/00 , B82Y5/00 , C12R1/24 , A23V2200/25
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公开(公告)号:EP2206505A1
公开(公告)日:2010-07-14
申请号:EP08790627.7
申请日:2008-06-26
申请人: Shinwa Pharmaceutical Co., Ltd. , Bio-Lab Ltd. , The Japanese Association Of Clinical Research on Supplements , Cosmo Foods Co., Ltd.
发明人: HASEGAWA, Hideo , KAN, Tatsuhiko
CPC分类号: C12N1/00 , A23K10/18 , A23L33/135 , A23V2002/00 , A23Y2220/13 , A61K8/99 , A61K35/747 , A61K2800/412 , A61Q19/00 , B82Y5/00 , C12R1/24 , A23V2200/25
摘要: Cells of lactic acid bacteria, which have been obtained by controlling pHs of media in a culturing step and processing steps to a neutral range of, for example, from 5 to 8 or so, have a mode value (particle size) of 1.0 µm or smaller in their particle size distribution. Cells of nano-sized lactic acid bacteria which have such a small particle size are excellent in INF-α producing capacity and are also superb in water dispersibility.
摘要翻译: 通过将培养步骤中的培养基的pH值和加工步骤达到例如5〜8左右的中性范围而获得的乳酸菌细胞的模式值(粒径)为1.0μm, 粒径分布较小。 具有如此小粒径的纳米级乳酸菌细胞的INF-生产能力优异,水分散性也极好。
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