公开(公告)号：EP4381961A1

公开(公告)日：2024-06-12

申请号：EP22853074.7

申请日：2022-08-02

申请人： AJINOMOTO CO., INC.

发明人： TOYAZAKI, Miku ,  HIRATANI, Moe ,  HAYASHI, Kazuyuki ,  SUZUKI, Masashi ,  YAHAGI, Daiki ,  USAMI, Riku ,  KURODA, Motonaka ,  MIZUNO, Masaki ,  SEKI, Toshihito ,  TAJIMA, Yoshinori

IPC分类号： A23L27/10 ,  A23L27/20 ,  A23L27/22 ,  A23L27/23 ,  C12N1/00

CPC分类号： A23L27/23 ,  A23L27/22 ,  C12N1/00 ,  A23L27/10 ,  A23L27/20

摘要： Provided is a technology for improving the flavor of food. The flavor of food is improved by adding the following ingredient (A):
(A) a cell wall-containing fraction of a gram-positive bacterium.

公开(公告)号：EP4365284A1

公开(公告)日：2024-05-08

申请号：EP22833318.3

申请日：2022-06-30

申请人： Asahi Kasei Medical Co., Ltd.

发明人： MIYAOKA, Rimi ,  TANIGUCHI, Hiroki ,  OKADA, Takashi

IPC分类号： C12N7/02 ,  B01D61/00 ,  B01D69/08 ,  C12N1/00 ,  C12N1/02

CPC分类号： C12N7/02 ,  B01D61/00 ,  B01D69/08 ,  C12N1/02 ,  C12N1/00

摘要： The purpose of the invention is to provide a virus recovery method including reducing viability of cells in a culture solution and filtering, through a hollow fiber membrane, the culture solution containing a virus produced by the cells to recover the virus. The hollow fiber membrane has a gradient structure in which an average pore size becomes smaller from an upstream side to a downstream side in a membrane thickness direction.

公开(公告)号：EP3225685B1

公开(公告)日：2018-12-12

申请号：EP16817969.5

申请日：2016-06-29

申请人： Sysmex Corporation

发明人： YOKOYAMA, Koji ,  OKA, Noriko ,  MORITA, Masakatsu ,  YAMAMOTO, Yuka

IPC分类号： C12N1/04 ,  C12N1/00 ,  C12N11/16 ,  C12Q1/04 ,  C12Q1/68 ,  G01N33/48 ,  G01N33/50 ,  C12N5/071 ,  C12N5/09

CPC分类号： A01N1/021 ,  C12N1/00 ,  C12N1/04 ,  C12N11/16 ,  C12Q1/04 ,  C12Q1/68 ,  G01N1/30 ,  G01N33/48 ,  G01N33/50 ,  G01N2001/305

摘要： The present invention relates to a cell preservative solution. Further, the present invention relates to a method of preserving cells, a method of preparing fixed cells, and a method of analyzing cells, using a cell preservative solution. Furthermore, the present invention relates to a method of producing a cell preservative solution.

公开(公告)号：EP1339829B1

公开(公告)日：2018-10-24

申请号：EP01991926.5

申请日：2001-11-06

申请人： Life Technologies Corporation

发明人： FIKE, Richard, Milton ,  HASSETT, Richard, Francis ,  DADEY, Barbara, Mary ,  RADOMINSKI, Robert, Chester

IPC分类号： C12N1/16 ,  C12N1/20 ,  C12N5/00

CPC分类号： C12N5/0018 ,  C12N1/00 ,  C12N2500/36 ,  C12N2500/60

摘要： The present invention relates generally to nutritive (e.g., cell culture) medium, medium supplement, media subgroup and buffer formulations. Specifically, the present invention provides powdered nutritive medium, medium supplement and medium subgroup formulations, particularly cell culture medium supplements (including powdered sera such as powdered fetal bovine seum (FBS)), medium subgroup formulations and cell culture media comprising necessary nutritive factors that facilitate the in vitro cultivation of cells. The invention further provides such powdered formulations that produce particular or desired final ionic and/or pH conditions upon reconstitution with a solvent. The invention is also directed to methods of production of these formulations, and also provides kits and methods for cultivation of prokaryotic and eukaryotic cells using these formulations.; The invention also relates to methods of producing sterile formulations, and to methods for producing dry cell powders. The invention also provides cell, media, media supplement, media subgroup and buffer powders produced by the methods of the invention.

公开(公告)号：EP3385359A1

公开(公告)日：2018-10-10

申请号：EP16870741.2

申请日：2016-11-30

申请人： Nippon Suisan Kaisha, Ltd.

发明人： SEKIGUCHI Takayoshi ,  OKITA Yuji ,  NISHIZAWA Yumiko

IPC分类号： C11B1/10 ,  C12N1/00 ,  C12N1/12 ,  C12P7/64 ,  C12R1/89

CPC分类号： C11B1/10 ,  C12N1/00 ,  C12N1/12 ,  C12P7/64 ,  C12P7/6427 ,  C12R1/89

摘要： Docosahexaenoic acid-containing oil containing docosahexaenoic acid in a concentration of 40 wt.% or more of the total weight of fatty acids in the oil, and having an endothermic peak temperature determined by differential scanning calorimetry (DSC) of 15°C or lower; a biomass including the same; and a method for producing docosahexaenoic acid-containing oil including obtaining a biomass by culturing microorganisms of the genus Aurantiochytrium capable of producing this docosahexaenoic acid-containing oil, recovering the biomass after culture, and extracting the oil from the biomass after recovery.

公开(公告)号：EP3202889A4

公开(公告)日：2018-05-30

申请号：EP15846038

申请日：2015-08-19

申请人： KANEKA CORP ,  NAT HOSPITAL ORGANIZATION

发明人： KATO TOMOHISA ,  KANEMURA YONEHIRO ,  SHOFUDA TOMOKO ,  FUKUSUMI HAYATO

IPC分类号： C12N1/00 ,  C12M1/00 ,  C12M3/00 ,  C12N5/07 ,  C12N5/0735 ,  C12N5/10

CPC分类号： C12N5/0018 ,  C12M1/00 ,  C12M3/00 ,  C12N1/00 ,  C12N5/0696 ,  C12N5/10 ,  C12N2501/998

摘要： It is an object of the present invention to provide a cell culture medium capable of enhancing cell growth efficiency without using feeder cells, in particular wherein the cell culture medium does not comprise serum. According to the present invention, a cell culture medium comprising fibrin 5 and Zeta polypeptide is provided.

公开(公告)号：EP3184657A4

公开(公告)日：2018-03-14

申请号：EP15833027

申请日：2015-08-24

申请人： COMPANÍA MINERA ZALDIVAR LTDA

发明人： ALVAREZ RODRÍGUEZ JUAN CARLOS

IPC分类号： C22B15/00 ,  C12N1/20 ,  C22B3/18

CPC分类号： C12N1/20 ,  C12N1/00 ,  C12R1/01 ,  C22B3/18 ,  C22B15/00 ,  C22B15/0071 ,  Y02P10/234

摘要： The present invention relates to a method for leaching secondary and primary sulphides of copper in a ferrous chloride medium with iron-oxidising bacteria adapted from the crushing of the mineral from the mine, comprising the steps of: mixing the mineral from the crushing with concentrated sulphuric acid; transporting the material mixed with sulphuric acid by means of a belt; adding a liquid leaching solution at an intermediate point during transport on the belt, said solution consisting of: iron (II) sulphate to reduce the redox potential of the solution-mineral mixture to values less than 550 mV Ag/AgCl; iron (III) sulphate; bacteria and archaea of the mesophile- and thermophile-type belonging to the genera Acidithiobacillus, Leptospirillum and Sulfulobos, previously adapted in an annexed bioreactor plant; and sodium chloride to produce a chlorinated environment in solutions. The method also comprises the subsequent steps of; heaping the material on head pads to rest for a specific amount of time depending on the mineralogical composition of the material or the operating conditions of the plant; during the resting step, injecting air warmed by a liquid/air exchange system, said air being injected through the lower part of the heap by means of fans; and leaching the heaped material by means of a flow of solutions having a low sulphuric acid content, with ferric ion, which contribute to performing the second step of solubilising the copper sulphides.

公开(公告)号：EP3260418A1

公开(公告)日：2017-12-27

申请号：EP16752519.5

申请日：2016-02-17

申请人： Ajinomoto Co., Inc. ,  Tokyo Institute of Technology

发明人： KISHINO, Mitsuhiro ,  KOJIMA, Hiroyuki ,  HOSONO, Hideo ,  HARA, Michikazu ,  KITANO, Masaaki ,  YOKOYAMA, Toshiharu ,  NUMAGUCHI, Toru ,  ITO, Munenobu ,  YAMADA, Kazuteru ,  NOGUCHI, Hiromi

IPC分类号： C01C1/02 ,  B01J27/24 ,  C01C1/04 ,  C12M1/00 ,  C12N1/00 ,  C12P1/00 ,  C12P7/02 ,  C12P7/40 ,  C12P13/04 ,  C12P19/04 ,  C12P21/00

CPC分类号： C12P13/08 ,  B01J21/066 ,  B01J23/02 ,  B01J23/462 ,  B01J27/24 ,  B01J35/0006 ,  B01J37/04 ,  B01J37/088 ,  C01C1/02 ,  C01C1/04 ,  C01C1/0411 ,  C01C1/0417 ,  C12M1/00 ,  C12M29/26 ,  C12N1/00 ,  C12P1/00 ,  C12P7/02 ,  C12P7/40 ,  C12P13/04 ,  C12P13/14 ,  C12P19/04 ,  C12P21/00 ,  Y02P20/52

摘要： Provided is a novel production system for a product selected from a nitrogen-containing product and a fermented and cultured product that does not involve (or can minimize) the transport of liquid ammonia.
A production system for a product selected from a nitrogen-containing product and a fermented and cultured product includes:
an ammonia synthesis apparatus in which an ammonia-containing gas is synthesized by reaction of a source gas containing hydrogen and nitrogen in the presence of a supported metal catalyst containing as a support one or more selected from the group consisting of: i) a conductive mayenite compound; ii) a two-dimensional electride compound or a precursor thereof; and iii) a complex formed of a support base containing at least one metal oxide selected from ZrO 2 , TiO 2 , CeO 2 , and MgO and a metal amide represented by a formula M(NH 2 ) x (where M represents one or more selected from Li, Na, K, Be, Mg, Ca, Sr, Ba, and Eu; and x represents a valence number of M) supported by the support base; and
a production apparatus that produces a product selected from a nitrogen-containing product and a fermented and cultured product using ammonia originating from the ammonia-containing gas obtained by using the ammonia synthesis apparatus.

摘要翻译： 提供了一种新型生产系统，用于从不含（或可以最小化）液态氨传输的含氮产品和发酵培养产品中选择的产品。 选自含氮产品和发酵培养产品的产品的生产系统包括：氨合成装置，其中通过含有氢和氮的源气体在受到支持的情况下反应合成含氨气体 金属催化剂，其含有选自以下的一种或多种作为载体：i）导电钙铝石化合物; ii）二维电子化合物或其前体; 和iii）由含有选自ZrO 2，TiO 2，CeO 2和MgO中的至少一种金属氧化物的载体基底和式M（NH 2）x（其中M表示选自Li， Na，K，Be，Mg，Ca，Sr，Ba和Eu;且x表示由载体基质支撑的M的化合价） 以及使用来自使用氨合成装置得到的含氨气体的氨的制造装置，其制造选自含氮产物和发酵培养物的产物。

公开(公告)号：EP3252150A1

公开(公告)日：2017-12-06

申请号：EP16743374.7

申请日：2016-01-26

申请人： UBE Industries, Ltd. ,  Kurume University

发明人： OHTA, Keisuke ,  HIRASHIMA, Shingo ,  HAGIHARA, Masahiko ,  SHIMIZU, Motohisa

IPC分类号： C12N5/077 ,  C08J9/00 ,  C12N1/00

CPC分类号： C12N5/0669 ,  A61L27/18 ,  A61L27/3608 ,  A61L27/56 ,  A61L2430/02 ,  C08J9/00 ,  C12N1/00 ,  C12N5/0647 ,  C12N2501/14 ,  C12N2533/30

摘要： The present invention relates to a method for culturing bone marrow cells, in which bone marrow cells are applied to a porous polyimide film and cultured. Moreover, the present invention relates to a porous polyimide film for healing a bone injury site.

摘要翻译： 骨髓细胞的培养方法技术领域本发明涉及骨髓细胞的培养方法，其中将骨髓细胞应用于多孔聚酰亚胺膜并进行培养。 此外，本发明涉及用于治疗骨损伤部位的多孔聚酰亚胺膜。

公开(公告)号：EP2718447B1

公开(公告)日：2017-08-23

申请号：EP12796103.5

申请日：2012-06-11

申请人： Integrated BioChem, LLC

发明人： CALT, Edward, Arthur, Jr. ,  TULL, Herbert, Graham ,  TOPOREK, Stanley, Sylvester

IPC分类号： C12P1/00 ,  C12P7/06 ,  C12P7/16 ,  C12P7/20 ,  C12P7/40 ,  C12P7/52 ,  C12P7/54 ,  C12P7/56 ,  C12P7/64 ,  C12P39/00 ,  C02F11/02 ,  C12M1/36 ,  C12M1/107

CPC分类号： C12P7/56 ,  C02F11/04 ,  C05F1/007 ,  C05F5/008 ,  C05F9/00 ,  C05F11/00 ,  C05F17/0027 ,  C05F17/0045 ,  C12M21/04 ,  C12M43/08 ,  C12M45/02 ,  C12N1/00 ,  C12P5/023 ,  C12P7/20 ,  C12P7/40 ,  C12P7/52 ,  C12P7/54 ,  C12P39/00 ,  Y02A40/201 ,  Y02A40/212 ,  Y02A40/214 ,  Y02E50/13 ,  Y02E50/17 ,  Y02E50/343 ,  Y02P20/145 ,  Y02W30/43 ,  Y02W30/47

摘要： The presently disclosed subject matter relates to Managed Ecosystem Fermentation (MEF) which is a continuous microbial process utilizing a managed ecosystem approach employing dozens to thousands of species of microorganisms, occurring in a controlled artificial environment and consuming organic materials without benefit of sterilization. The process of utilizing this fermentation for the consumption of organic materials on a continuous basis is within the scope of this disclosed subject matter. The process of separating chemicals as industrial chemicals from this fermentation on a continuous basis is within the scope of this disclosed subject matter. The process of separating biomass useful as high protein animal feed or fertilizer from this fermentation on a continuous (or semi-continuous) basis is within the scope of this disclosed subject matter.

摘要翻译： 目前公开的主题涉及管理生态系统发酵（MEF），其是利用管理生态系统方法的连续微生物过程，其采用数十至数千种微生物物种，发生在受控的人造环境中并消耗有机材料而无需消毒。 利用这种发酵连续消耗有机物质的方法在本发明的范围内。 从该发酵中持续分离化学品作为工业化学品的过程在本公开主题的范围内。 在连续（或半连续）基础上从该发酵中分离可用作高蛋白动物饲料或肥料的生物质的方法在本公开主题的范围内。