公开(公告)号：EP4410292A1

公开(公告)日：2024-08-07

申请号：EP22876159.9

申请日：2022-09-27

申请人： Shionogi & Co., Ltd ,  National University Corporation Hokkaido University

发明人： TACHIBANA Yuki ,  UEHARA Shota ,  UNOH Yuto ,  NAKAHARA Kenji ,  TAODA Yoshiyuki ,  KASAMATSU Koji ,  YAMATSU Yukiko ,  ANDO Shigeru ,  FUKAO Keita ,  NOBORI Haruaki ,  KURODA Takayuki ,  TOBA Shinsuke ,  UEMURA Kentaro ,  MARUYAMA Yuki ,  SASAKI Michihito ,  SAWA Hirofumi

IPC分类号： A61K31/5355 ,  A61K31/53 ,  A61K31/5377 ,  A61P31/12 ,  A61P31/14 ,  A61P43/00

CPC分类号： A61P31/12 ,  A61P43/00 ,  A61K31/5355 ,  A61K31/5377 ,  A61K31/53 ,  A61P31/14

摘要： The present invention provides a pharmaceutical composition comprising a compound exhibiting coronavirus proliferation inhibitory activity.

A pharmaceutical composition comprising a compound represented by the formula: wherein Y is N; R1 is substituted or unsubstituted aromatic heterocyclyl; R2 is substituted or unsubstituted 6-membered aromatic carbocyclyl; R3 is substituted or unsubstituted aromatic heterocyclyl; -X- is -NH-; m is 0 or 1; R5a is a hydrogen atom; R5b is a hydrogen atom; n is 1; R4a is a hydrogen atom; and R4b is a hydrogen atom, or a pharmaceutically acceptable salt thereof.