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    AGENT FOR SEDATING RESPONSE TO EXTERNAL STIMULATION IN SKIN AND METHOD FOR SEDATING THAT RESPONSE TECHNICAL FIELD
    2.
    发明公开
    AGENT FOR SEDATING RESPONSE TO EXTERNAL STIMULATION IN SKIN AND METHOD FOR SEDATING THAT RESPONSE TECHNICAL FIELD 有权
    MEANS镇静应对外部刺激对镇静这种反应在皮肤和方法

    公开(公告)号：EP2941254A1

    公开(公告)日：2015-11-11

    申请号：EP14715531.1

    申请日：2014-03-12

    申请人： Shiseido Company Ltd.

    发明人： HOSOI, Junichi ,  INOUE, Kaori ,  YAMADA, Shoko ,  SATO, Minako

    IPC分类号： A61K31/716 ,  A61K31/77 ,  A61K36/73 ,  A61P17/00

    CPC分类号： A61K31/716 ,  A61K31/77 ,  A61K36/738 ,  A61K2300/00

    摘要： An object of the present invention is to provide an agent for sedating the response of skin to external stimulation. The aforementioned object was achieved by finding a component that promotes CD39 gene expression in Langerhans cells. More specifically, the present invention is based on the finding that the combination of carboxymethyl-beta glucan or a salt thereof, polyoxyethylene (POE)/polyoxypropylene (POP) random copolymer dimethyl ether and rosewater promotes CD39 gene expression.

    摘要翻译： 本发明的一个目的是提供一种用于皮肤镇静的对外界刺激的响应提供的试剂。 上述目的什么通过找到一个部件取得确实促进在朗格汉斯细胞CD39的基因表达。 更具体地，本发明是基于这样的发现所做羧甲基β葡聚糖或其聚氧乙烯（POE）/聚氧化丙烯（POP）无规共聚物二甲醚和玫瑰水促进CD39基因表达的盐的组合。