公开(公告)号：EP4295856A1

公开(公告)日：2023-12-27

申请号：EP21926606.1

申请日：2021-02-19

申请人： Shiseido Company, Ltd.

发明人： HOSOI, Junichi ,  HASEGAWA, Tatsuya

IPC分类号： A61K36/185 ,  A61P17/00 ,  A61P37/04 ,  A61P43/00 ,  A23L33/105 ,  A61K8/9789 ,  A61Q19/08

摘要： The present invention provides an immune cell activator containing hibiscus or a fermented extract thereof as an active ingredient. The present invention also provides an anti-aging agent characterized in that said anti-aging agent contains hibiscus or a fermented extract thereof as an active ingredient and eliminates senescent cells by activating immune cells. The present invention additionally provides a method for activating immune cells in a subject in need thereof, wherein the method includes administering hibiscus or a fermented extract thereof to the subject and activating the immune cells thereof. In addition, the present invention provides a method for preventing or protecting against aging in a subject in need thereof, wherein the method includes administering hibiscus or a fermented extract thereof to the subject and eliminating senescent cells by activating immune cells.

公开(公告)号：EP2941254B1

公开(公告)日：2017-01-11

申请号：EP14715531.1

申请日：2014-03-12

申请人： Shiseido Company, Ltd.

发明人： HOSOI, Junichi ,  INOUE, Kaori ,  YAMADA, Shoko ,  SATO, Minako

IPC分类号： A61K31/716 ,  A61K31/77 ,  A61K36/738 ,  A61P17/00

CPC分类号： A61K31/716 ,  A61K31/77 ,  A61K36/738 ,  A61K2300/00

公开(公告)号：EP4140544A1

公开(公告)日：2023-03-01

申请号：EP21792866.2

申请日：2021-04-19

申请人： Shiseido Company, Ltd.

发明人： HORIBA, Satoshi ,  HOSOI, Junichi ,  INOUE, Daigo ,  KAJIYA, Kentaro ,  TAKAGI, Masaya ,  MATSUURA, Yuko ,  IINO, Masato

IPC分类号： A61Q17/04 ,  A61Q19/00 ,  A61Q19/08 ,  A61H23/02 ,  A61K8/9761

摘要： The present invention provides an agent for preventing and/or improving photoaging and/or dermal pigmentation comprising Thujae Semen extract as an active ingredient. The present invention also provides a cosmetic method which includes a step for applying the agent for preventing and/or improving photoaging and/or dermal pigmentation to skin to be treated, and a cosmetic device to be applied in said method.

公开(公告)号：EP2941254A1

公开(公告)日：2015-11-11

申请号：EP14715531.1

申请日：2014-03-12

申请人： Shiseido Company Ltd.

发明人： HOSOI, Junichi ,  INOUE, Kaori ,  YAMADA, Shoko ,  SATO, Minako

IPC分类号： A61K31/716 ,  A61K31/77 ,  A61K36/73 ,  A61P17/00

CPC分类号： A61K31/716 ,  A61K31/77 ,  A61K36/738 ,  A61K2300/00

摘要： An object of the present invention is to provide an agent for sedating the response of skin to external stimulation. The aforementioned object was achieved by finding a component that promotes CD39 gene expression in Langerhans cells. More specifically, the present invention is based on the finding that the combination of carboxymethyl-beta glucan or a salt thereof, polyoxyethylene (POE)/polyoxypropylene (POP) random copolymer dimethyl ether and rosewater promotes CD39 gene expression.

摘要翻译： 本发明的一个目的是提供一种用于皮肤镇静的对外界刺激的响应提供的试剂。 上述目的什么通过找到一个部件取得确实促进在朗格汉斯细胞CD39的基因表达。 更具体地，本发明是基于这样的发现所做羧甲基β葡聚糖或其聚氧乙烯（POE）/聚氧化丙烯（POP）无规共聚物二甲醚和玫瑰水促进CD39基因表达的盐的组合。