公开(公告)号：EP4295856A1

公开(公告)日：2023-12-27

申请号：EP21926606.1

申请日：2021-02-19

申请人： Shiseido Company, Ltd.

发明人： HOSOI, Junichi ,  HASEGAWA, Tatsuya

IPC分类号： A61K36/185 ,  A61P17/00 ,  A61P37/04 ,  A61P43/00 ,  A23L33/105 ,  A61K8/9789 ,  A61Q19/08

摘要： The present invention provides an immune cell activator containing hibiscus or a fermented extract thereof as an active ingredient. The present invention also provides an anti-aging agent characterized in that said anti-aging agent contains hibiscus or a fermented extract thereof as an active ingredient and eliminates senescent cells by activating immune cells. The present invention additionally provides a method for activating immune cells in a subject in need thereof, wherein the method includes administering hibiscus or a fermented extract thereof to the subject and activating the immune cells thereof. In addition, the present invention provides a method for preventing or protecting against aging in a subject in need thereof, wherein the method includes administering hibiscus or a fermented extract thereof to the subject and eliminating senescent cells by activating immune cells.

公开(公告)号：EP3175860A1

公开(公告)日：2017-06-07

申请号：EP15827114.8

申请日：2015-07-30

申请人： Shiseido Company Ltd.

发明人： FUKADA, Kaedeko ,  HASEGAWA, Tatsuya ,  MORI, Hiroshi ,  SUZUKI, Yoshiharu

IPC分类号： A61K36/23 ,  A61P3/10 ,  A61P9/00 ,  A61P9/10 ,  A61P11/00 ,  A61P17/06 ,  A61P21/00 ,  A61P25/00 ,  A61P25/14 ,  A61P25/28 ,  A61P35/00 ,  A61P43/00

CPC分类号： A61K36/23 ,  A61K2236/15 ,  A61K2236/17 ,  A61K2236/333 ,  A61K2236/53

摘要： The present invention provides a novel sirtuin-1 activating agent, and a formulation for suppressing cell senescence caused by oxidative stress, comprising the agent.
In particular, the invention provides a sirtuin-1 activating agent consisting of a plant body or solvent extract of Peucedanum japonicum Thunb., and a formulation for suppressing cell senescence due to oxidative stress, comprising the agent.

摘要翻译： 本发明提供了一种新颖的瑟土因-1活化剂和用于抑制由氧化应激引起的细胞衰老的制剂，其包含所述活性剂。 具体而言，本发明提供了由日本刺胡中的植物体或溶剂提取物组成的瑟土因-1活化剂和用于抑制由于氧化应激导致的细胞衰老的制剂。