公开(公告)号：EP3519426A1

公开(公告)日：2019-08-07

申请号：EP17868131.8

申请日：2017-10-31

申请人： Singapore Health Services Pte Ltd ,  Nanyang Technological University

发明人： RAJAMANI, Lakshminarayanan ,  MAYANDI, Venkatesh ,  GOH, Tze Leng Eunice ,  BEUERMAN, Roger Wilmer ,  VERMA, Navin Kumar

IPC分类号： C07K14/00 ,  C07K7/02 ,  A61K38/08 ,  A61P31/04

公开(公告)号：EP3319779A1

公开(公告)日：2018-05-16

申请号：EP16821928.5

申请日：2016-07-06

申请人： Singapore Health Services Pte Ltd ,  National University of Singapore

发明人： RAJAMANI, Lakshminarayanan ,  DHAND, Chetna ,  RAMAKRISHNA, Seeram ,  LIU, Shouping ,  BEUERMAN, Roger Wilmer

IPC分类号： B29C47/00

CPC分类号： A61F13/53 ,  C08G63/08 ,  C08K3/10 ,  C08K5/175 ,  C08L5/08 ,  C08L71/02 ,  C08L77/04 ,  C08L2203/12 ,  D01D5/003 ,  D01F1/10 ,  D01F1/103 ,  D01F11/00 ,  D01F11/02 ,  D01F11/06 ,  D01F11/08

摘要： The present invention provides a polymer product and a method for preparing the polymer product comprising electrospinning from a dope solution comprising at least one polymer and at least one cross-linking agent to prepare and/or fabricate the polymer product. In certain embodiments, the cross-linking agent comprises at least one catecholamine or at least one polyphenol, wherein the method comprises (i) electrospinning the biocompatible polymer product using a dope solution comprising a polymer and at least one catecholamine or at least one polyphenol and (ii) exposing the polymer product to at least one gaseous alkaline reagent. The dope solutions and polymer products of the invention can further include antimicrobial agents, metal ions, and other substances.

公开(公告)号：EP3600306A1

公开(公告)日：2020-02-05

申请号：EP18772076.8

申请日：2018-03-22

申请人： Singapore Health Services Pte Ltd ,  Santen Pharmaceutical Co., Ltd.

发明人： TAN, Tiang Hwee Donald ,  BEUERMAN, Roger Wilmer ,  SAW, Seang-Mei ,  UPADHYAY, Aradhana ,  KATO, Masatomo ,  INABA, Takaaki

IPC分类号： A61K31/439 ,  A61P27/10

公开(公告)号：EP2892913A1

公开(公告)日：2015-07-15

申请号：EP13834422.1

申请日：2013-09-09

申请人： Agency for Science, Technology and Research ,  Singapore Health Services Pte Ltd

发明人： CHANDRA SHEKHAR, Verma ,  LI, Jianguo ,  RAJAMANI, Lakshminarayanan ,  BEUERMAN, Roger Wilmer ,  LIU, Shouping ,  KOH, Jun Jie

IPC分类号： C07K14/00 ,  C07K7/00 ,  A61K38/04 ,  A61K38/10 ,  A61K38/16 ,  A61P31/04 ,  A61P31/10 ,  A61L12/14

CPC分类号： C07K14/00 ,  A61K38/00 ,  C07K7/08 ,  Y02A50/475 ,  Y02A50/492

摘要： Disclosed are antimicrobial peptides. Also disclosed are methods of treating bacterial infection and fungal infection and a method of removing biofilm. Also disclosed is the use of these peptides.