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公开(公告)号：EP4366772A1
公开(公告)日：2024-05-15
申请号：EP22838435.0
申请日：2022-07-07
申请人： Singh Biotechnology, LLC , The United States of America, as represented by the Secretary, Department of Health and Human Services
发明人： SINGH, Sunanda , EGWUAGU, Charles
IPC分类号： A61K39/395 , A61P27/02
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公开(公告)号：EP4392459A2
公开(公告)日：2024-07-03
申请号：EP22862293.2
申请日：2022-08-26
发明人： SINGH, Sunanda
IPC分类号： C07K16/40
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公开(公告)号：EP3209685B1
公开(公告)日：2019-04-24
申请号：EP15853465.1
申请日：2015-10-23
发明人： SINGH, Sunanda
IPC分类号： C07K16/18 , A61K39/395
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公开(公告)号：EP3371215A2
公开(公告)日：2018-09-12
申请号：EP16862887.3
申请日：2016-11-02
发明人： SINGH, Sunanda
IPC分类号： C07K16/10 , A61K39/42 , A61K39/395 , A61K38/55 , G01N33/68 , G01N33/563 , G01N33/53 , A61P31/18
CPC分类号： A61K45/06 , A61K39/42 , A61K2039/505 , A61P31/12 , C07K16/1045 , C07K16/40 , C07K2317/22 , C07K2317/34 , C07K2317/569 , C07K2317/92 , G01N33/56983 , G01N33/573 , G01N2333/08 , G01N2333/9128 , G01N2469/10
摘要： This invention provides compositions and methods to treat a condition or disease without the use of exogenous targeting sequences or chemical compositions. The present invention relates to single-domain antibodies (sdAbs), proteins and polypeptides comprising the sdAbs that are directed against targets that cause a condition or disease. The invention also includes nucleic acids encoding the sdAbs, proteins and polypeptides, and compositions comprising the sdAbs. The invention includes the use of the compositions, sdAbs, and nucleic acids encoding the sdAbs for prophylactic, therapeutic or diagnostic purposes.
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公开(公告)号：EP3209685A2
公开(公告)日：2017-08-30
申请号：EP15853465.1
申请日：2015-10-23
发明人： SINGH, Sunanda
IPC分类号： C07K16/18 , A61K39/395
CPC分类号： C07K16/241 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , C07K16/18 , C07K16/3015 , C07K16/303 , C07K16/3069 , C07K16/32 , C07K16/40 , C07K16/42 , C07K16/4241 , C07K2317/569 , C07K2317/73 , C07K2317/76 , C07K2317/92 , G01N33/574 , G01N33/6854 , G01N33/686 , G01N33/6872 , G01N33/94
摘要： This invention provides compositions and methods to treat a condition or disease without the use of exogenous targeting sequences or chemical compositions. The present invention relates to single-domain antibodies (sdAbs), proteins and polypeptides comprising the sdAbs that are directed against intracellular components that cause a condition or disease. The invention also includes nucleic acids encoding the sdAbs, proteins and polypeptides, and compositions comprising the sdAbs. The invention includes the use of the compositions, sdAbs, and nucleic acids encoding the sdAbs for prophylactic, therapeutic or diagnostic purposes.
摘要翻译： 本发明提供了在不使用外源靶向序列或化学组合物的情况下治疗病症或疾病的组合物和方法。 本发明涉及针对导致病症或疾病的细胞内成分的单域抗体（sdAb），包含sdAb的蛋白质和多肽。 本发明还包括编码sdAb的核酸，蛋白质和多肽以及包含sdAb的组合物。 本发明包括组合物，sdAb和编码sdAb的核酸用于预防，治疗或诊断目的的用途。
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