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公开(公告)号：EP1618889A3
公开(公告)日：2006-06-14
申请号：EP05077465.2
申请日：2000-09-27
发明人： D'Hondt, Erik , Hehme, Norbert
IPC分类号： A61K39/145 , A61P31/12
CPC分类号： C12N7/00 , A61K39/12 , A61K39/145 , A61K2039/5252 , A61K2039/54 , A61K2039/543 , A61K2039/55505 , C07K14/005 , C12N2760/16122 , C12N2760/16151 , C12N2760/16222 , C12N2760/16234 , C12N2760/16251
摘要： The invention provides a monovalent influenza vaccine comprising a low dose of egg-derived influenza virus antigen from an influenza virus strain that is associated with a pandemic outbreak or has the potential to be associated with a pandemic outbreak, in combination with an aluminium adjuvant. The invention also provides vaccine kits comprising a combination of a parenteral and a mucosal influenza vaccine, wherein the combined dose of antigen is no more than the conventional antigen dose. Also provided are methods for preparing the vaccines.
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公开(公告)号：EP2269637A1
公开(公告)日：2011-01-05
申请号：EP10178205.0
申请日：2000-09-27
发明人： D'Hondt, Erik , Hehme, Norbert
IPC分类号： A61K39/145 , A61P31/12
CPC分类号： C12N7/00 , A61K39/12 , A61K39/145 , A61K2039/5252 , A61K2039/54 , A61K2039/543 , A61K2039/55505 , C07K14/005 , C12N2760/16122 , C12N2760/16151 , C12N2760/16222 , C12N2760/16234 , C12N2760/16251
摘要： The invention provides a monovalent influenza vaccine comprising a low dose of egg-derived influenza virus antigen from an influenza virus strain that is associated with a pandemic outbreak or has the potential to be associated with a pandemic outbreak, in combination with an aluminium adjuvant. The invention also provides vaccine kits comprising a combination of a parenteral and a mucosal influenza vaccine, wherein the combined dose of antigen is no more than the conventional antigen dose. Also provided are methods for preparing the vaccines.
摘要翻译： 本发明提供了一种单价流感疫苗，其包含来自与流行性感冒爆发有关或可能与大流行病暴发相关的流感病毒毒株的低剂量鸡蛋来源的流感病毒抗原与铝佐剂组合。 本发明还提供包含肠胃外和粘膜流感疫苗组合的疫苗试剂盒，其中抗原的组合剂量不超过常规抗原剂量。 还提供了用于制备疫苗的方法。
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公开(公告)号：EP1618889B1
公开(公告)日：2011-02-23
申请号：EP05077465.2
申请日：2000-09-27
发明人： D'Hondt, Erik , Hehme, Norbert
IPC分类号： A61K39/145 , A61P31/12
CPC分类号： C12N7/00 , A61K39/12 , A61K39/145 , A61K2039/5252 , A61K2039/54 , A61K2039/543 , A61K2039/55505 , C07K14/005 , C12N2760/16122 , C12N2760/16151 , C12N2760/16222 , C12N2760/16234 , C12N2760/16251
摘要： The invention provides a monovalent influenza vaccine comprising a low dose of egg-derived influenza virus antigen from an influenza virus strain that is associated with a pandemic outbreak or has the potential to be associated with a pandemic outbreak, in combination with an aluminium adjuvant. The invention also provides vaccine kits comprising a combination of a parenteral and a mucosal influenza vaccine, wherein the combined dose of antigen is no more than the conventional antigen dose. Also provided are methods for preparing the vaccines.
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公开(公告)号：EP1618889A2
公开(公告)日：2006-01-25
申请号：EP05077465.2
申请日：2000-09-27
发明人： D'Hondt, Erik , Hehme, Norbert
IPC分类号： A61K39/145 , A61P31/12
CPC分类号： C12N7/00 , A61K39/12 , A61K39/145 , A61K2039/5252 , A61K2039/54 , A61K2039/543 , A61K2039/55505 , C07K14/005 , C12N2760/16122 , C12N2760/16151 , C12N2760/16222 , C12N2760/16234 , C12N2760/16251
摘要： The invention provides a monovalent influenza vaccine comprising a low dose of egg-derived influenza virus antigen from an influenza virus strain that is associated with a pandemic outbreak or has the potential to be associated with a pandemic outbreak, in combination with an aluminium adjuvant. The invention also provides vaccine kits comprising a combination of a parenteral and a mucosal influenza vaccine, wherein the combined dose of antigen is no more than the conventional antigen dose. Also provided are methods for preparing the vaccines.
摘要翻译： 本发明提供了一种单价流感疫苗，其包含与流感病毒毒株相关的低剂量的来自流感病毒毒株的流感病毒抗原，其与大流行性流感爆发相关联，或者与铝佐剂组合可能与大流行性流感相关。 本发明还提供包含肠胃外和粘膜流感疫苗的组合的疫苗试剂盒，其中抗原的组合剂量不超过常规抗原剂量。 还提供了用于制备疫苗的方法。
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