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公开(公告)号：EP1482930A1
公开(公告)日：2004-12-08
申请号：EP03744644.0
申请日：2003-03-12
发明人： AUBART, Kelly, M. , BHAT, Ajita , CHRISTENSEN, IV, Siegfried, B. , LEBER, Jack, Dale , LIAO, Xiangmin
IPC分类号： A61K31/4166 , C07D233/78
CPC分类号： C07D233/76 , C07D233/78 , C07D409/06 , C07D409/12
摘要： Novel PDF inhibitors and novel methods for their use are provided.
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公开(公告)号：EP1490047B1
公开(公告)日：2009-12-30
申请号：EP03719457.8
申请日：2003-03-26
发明人： THOMPSON, Scott, K. , FRAZEE, James, S. , KALLANDER, Lara, S. , MA, Chum , MARINO, Joseph, P. , NEEB, Michael, J. , BHAT, Ajita
IPC分类号： A61K31/34 , A61K31/38 , A61K31/40 , C07D209/14 , C07D209/16 , C07D307/81 , C07D333/58 , C07D407/12 , A61P9/00
CPC分类号： C07D307/81 , C07D307/79 , C07D407/12
摘要： Disclosed is a compound of having the formula: (I) pharmaceutically acceptable salts or solvates thereof and pharmaceutical compositions containing the same, wherein the structural variables are as defined herein. The compounds, salts and solvates of this invention are useful as LXR agonists.
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公开(公告)号：EP1383736B1
公开(公告)日：2009-06-17
申请号：EP02770378.4
申请日：2002-04-04
发明人： BHAT, Ajita , CHRISTENSEN, IV, Siegfried, B. , FRAZEE, James, S. , HEAD, Martha, S. , LEBER, Jack, Dale , LI, Mei
IPC分类号： C07C259/04 , C07C229/38
CPC分类号： C07D207/26 , C07C259/06 , C07D207/38 , C07D207/416 , C07D213/30 , C07D333/16
摘要： PDF inhibitors and novel methods for their use are provided.
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公开(公告)号：EP1575495A2
公开(公告)日：2005-09-21
申请号：EP03745638.1
申请日：2003-03-26
发明人： THOMPSON, Scott, K. , FRAZEE, James, S. , KALLANDER, Lara, S. , MA, Chun , MARINO, Joseph, P. , NEEB, Michael, J. , BHAT, Ajita , MCATEE, John, Jeffrey , STAVENGER, Robert, A.
IPC分类号： A61K6/00
CPC分类号： C07C311/29 , C07C217/18 , C07C217/20 , C07C217/22 , C07C217/36 , C07C219/22 , C07C229/34 , C07C233/25 , C07C271/28 , C07C275/34 , C07C291/02 , C07C309/73 , C07C311/08 , C07C311/09 , C07C311/21 , C07C323/32 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07D211/34 , C07D211/60 , C07D213/38 , C07D213/64 , C07D213/74 , C07D231/14 , C07D233/64 , C07D239/42 , C07D249/08 , C07D257/04 , C07D295/096 , C07D295/125 , C07D295/185 , C07D307/66 , C07D307/68 , C07D317/58 , C07D317/68 , C07D319/18 , C07D333/20
摘要： Disclosed is a compound having the formula (I) pharmaceutically acceptable salts or solvates thereof and pharmaceutical compositions containing the same, wherein the structural variables are as defined herein. The compounds, salts and solvates of this invention are useful as LXR agonists.
摘要翻译： 公开了具有下式的化合物：其药学上可接受的盐或溶剂合物和含有该化合物的药物组合物，其中结构变量如本文所定义。 本发明的化合物，盐和溶剂化物可用作LXR激动剂。
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公开(公告)号：EP1490047A2
公开(公告)日：2004-12-29
申请号：EP03719457.8
申请日：2003-03-26
发明人： THOMPSON, Scott, K. , FRAZEE, James, S. , KALLANDER, Lara, S. , MA, Chum , MARINO, Joseph, P. , NEEB, Michael, J. , BHAT, Ajita
IPC分类号： A61K31/34 , A61K31/38 , A61K31/40 , C07D209/14 , C07D209/16 , C07D307/81 , C07D333/58
CPC分类号： C07D307/81 , C07D307/79 , C07D407/12
摘要： Disclosed is a compound of having the formula: (I) pharmaceutically acceptable salts or solvates thereof and pharmaceutical compositions containing the same, wherein the structural variables are as defined herein. The compounds, salts and solvates of this invention are useful as LXR agonists.
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公开(公告)号：EP1383736A2
公开(公告)日：2004-01-28
申请号：EP02770378.4
申请日：2002-04-04
发明人： BHAT, Ajita , CHRISTENSEN, IV, Siegfried, B. , FRAZEE, James, S. , HEAD, Martha, S. , LEBER, Jack, Dale , LI, Mei
IPC分类号： C07C259/04 , C07C229/38
CPC分类号： C07D207/26 , C07C259/06 , C07D207/38 , C07D207/416 , C07D213/30 , C07D333/16
摘要： PDF inhibitors and novel methods for their use are provided.
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公开(公告)号：EP1383729A1
公开(公告)日：2004-01-28
申请号：EP02721667.0
申请日：2002-04-04
发明人： BHAT, Ajita , CHRISTENSEN, Siegfried, B., IV , FRAZEE, James, S. , HEAD, Martha, S. , LEBER, Jack, Dale , LI, Mei
IPC分类号： C07C229/00 , C07C62/00 , C07C261/00 , C07D257/12 , C07D207/00 , C07D239/00 , C07D277/08 , C07D209/02 , C07D233/00 , C07D231/00
CPC分类号： C07C259/06 , C07C2601/02
摘要： PDF inhibitors and novel methods for their use are provided.
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