公开(公告)号：EP1242081A1

公开(公告)日：2002-09-25

申请号：EP00965555.6

申请日：2000-09-29

申请人： SmithKline Beecham Corporation

发明人： LEE, Dennis ,  LONG, Scott, A. ,  ELLIOTT, John, D. ,  GLEASON, John, G.

IPC分类号： A61K31/445 ,  A61K31/44 ,  A61K31/40

CPC分类号： A61K31/403

摘要： The present invention is to the novel compounds of Formula (I), their pharmaceutical compositions, and to the novel inhibition of caspases for use in the treatment of apoptosis, and disease states caused by excessive or inappropriate cell death.

公开(公告)号：EP1001933A1

公开(公告)日：2000-05-24

申请号：EP98939143.8

申请日：1998-07-30

申请人： SMITHKLINE BEECHAM CORPORATION

发明人： LEE, Dennis ,  LONG, Scott, A.

IPC分类号： C07D209/02 ,  C07D209/36 ,  C07D251/18 ,  C07D251/48 ,  C07D473/00 ,  C07D413/00 ,  A61K31/535 ,  A61K31/445 ,  A61K31/44 ,  A61K31/40

CPC分类号： C07D209/38

摘要： The present invention is to the novel compounds of Formula (I), their pharmaceutical compositions, and to the novel inhibition of caspases for use in the treatment of apoptosis, and disease states caused by excessive or inappropriate cell death.

公开(公告)号：EP0988035B1

公开(公告)日：2003-05-02

申请号：EP98939138.8

申请日：1998-07-30

申请人： SMITHKLINE BEECHAM CORPORATION

发明人： LEE, Dennis ,  LONG, Scott, A.

IPC分类号： A61K31/40 ,  C07D209/34 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12

CPC分类号： C07D401/12 ,  C07D209/34 ,  C07D223/14 ,  C07D403/12 ,  C07D405/12