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    System for controlling and adjusting interstitial photodynamic light therapy parameters
    2.
    发明公开
    System for controlling and adjusting interstitial photodynamic light therapy parameters 有权
    系统on ung on n n n n n n n n n n n n n n n

    公开(公告)号：EP2431072A1

    公开(公告)日：2012-03-21

    申请号：EP11190657.4

    申请日：2007-08-15

    申请人： SpectraCure AB

    发明人： Svanberg, Sune ,  Andersson-Engels, Stefan ,  Johansson, Ann ,  Axelsson, Johan ,  Swartling, Johannes

    IPC分类号： A61N5/06 ,  A61B18/00 ,  A61B18/20 ,  A61B19/00

    CPC分类号： A61N5/062 ,  A61B2017/00022 ,  A61B2018/00642 ,  A61B2034/105 ,  A61N5/0601 ,  A61N2005/0612 ,  A61N2005/063

    摘要： A method and system for controlling and adjusting light in interstitial photodynamic light therapy (IPDT) in a subject is disclosed. More particularly, a method for controlling the light in interstitial tumor photodynamic light therapy is described using a calculation method for determination of status of tissue during the PDT treatment. The status is used in a feedback loop to control the continued PDT treatment. Methods are disclosed that constitute pre-treatment and realtime dosimetry modules for IPDT on the whole prostate glandular tissue. The method includes reconstruction of the target geometry, optimization of source fiber positions within this geometry, monitoring of the light attenuation during the treatment procedure and updating individual fiber irradiation times to take into account any variation in tissue light transmission. A control device that is arranged to restrict delivery of therapeutic light treatment at least temporary in dependence of at least one attribute of one of photodynamic treatment parameters. In comparison to no treatment feedback, a significant undertreatment of the patient as well as damage to healthy organs at risk are avoided.

    摘要翻译： 公开了一种用于控制和调节受试者中的间质性光动力光疗法（IPDT）中的光的方法和系统。 更具体地，使用用于在PDT处理期间确定组织状态的计算方法来描述用于控制间质肿瘤光动力光疗法中的光的方法。 该状态用于反馈回路以控制持续的PDT治疗。 公开了构成用于IPDT对整个前列腺腺组织的预处理和实时剂量测定模块的方法。 该方法包括重建目标几何形状，优化在该几何形状内的源光纤位置，监测处理过程中的光衰减和更新各个光纤照射时间以考虑到组织光透射中的任何变化。 一种控制装置，其被配置为根据光动力学治疗参数之一的至少一个属性至少临时地限制治疗性光处理的递送。 与没有治疗反馈相比，避免了对患者的重大治疗以及危及健康器官的损害。

    SYSTEM AND METHOD FOR DISTRIBUTING RADIATION FOR DIAGNOSTICS
    3.
    发明公开
    SYSTEM AND METHOD FOR DISTRIBUTING RADIATION FOR DIAGNOSTICS 审中-公开

    公开(公告)号：EP3915463A1

    公开(公告)日：2021-12-01

    申请号：EP20177487.4

    申请日：2020-05-29

    申请人： SpectraCure AB

    发明人： Swartling, Johannes ,  Soto Thompson, Marcelo ,  Grönlund, Rasmus

    IPC分类号： A61B5/00 ,  A61N5/06

    摘要： A system an d method of coupling light in and out of an optical member is described which includes transmitting at least one light beam within a wavelength range of infrared, visible or ultraviolet light using a light source; coupling the light beam into a proximal end of the optical member by means of at least one focussing optical component; collecting backscattered light using a distal end of the optical member and emitting the collected light at the proximal end of the optical member and wherein the light emitted by the optical member has at least partially a different angular sector than an angular sector of the light beam being coupled into the proximal end of the optical member, and detecting the collected light emitted from the proximal end of the optical member using at least one light detector.

    SYSTEM AND METHOD FOR DETERMINING LIGHT ATTENUATION AT OPTICAL MEMBERS INSERTED IN TISSUE
    5.
    发明公开
    SYSTEM AND METHOD FOR DETERMINING LIGHT ATTENUATION AT OPTICAL MEMBERS INSERTED IN TISSUE 审中-公开

    公开(公告)号：EP3718600A1

    公开(公告)日：2020-10-07

    申请号：EP19167324.3

    申请日：2019-04-04

    申请人： SpectraCure AB

    发明人： Swartling, Johannes ,  Arvidsson, Ida ,  Axelsson, Johan

    IPC分类号： A61N5/06 ,  A61B18/22

    摘要： A system and method for determining or estimating the presence and effect of light-attenuating inhomogeneities in tissue when performing medical treatment or diagnostics using optical members in tissue. The system and method comprising inserting a plurality of optical members into the tissue, and then measuring by emitting light through a sub-set of optical members at a time, while measuring the light collected by another sub-set of optical members. Combining said measurement data with a model for light propagation in tissue, and setting up a system of equations. Solving the unknown attenuation values from said system of equations.

    System for controlling and adjusting interstitial photodynamic light therapy parameters
    6.
    发明公开
    System for controlling and adjusting interstitial photodynamic light therapy parameters 有权
    System zurÜberwachungund Anpassung der Parameter de intrakorporalen optoynamischen Lichttherapie

    公开(公告)号：EP2298413A1

    公开(公告)日：2011-03-23

    申请号：EP10162517.6

    申请日：2007-08-15

    申请人： Spectracure AB

    发明人： Swartling, Johannes

    IPC分类号： A61N5/06 ,  A61B18/00 ,  A61B18/20 ,  A61B19/00

    CPC分类号： A61N5/062 ,  A61B2017/00022 ,  A61B2018/00642 ,  A61B2034/105 ,  A61N5/0601 ,  A61N2005/0612 ,  A61N2005/063

    摘要： A method and system for controlling and adjusting light in interstitial photodynamic light therapy (IPDT) in a subject is disclosed. More particularly, a method for controlling the light in interstitial tumor photodynamic light therapy is described using a calculation method for determination of status of tissue during the PDT treatment. The status is used in a feedback loop to control the continued PDT treatment. Methods are disclosed that constitute pre-treatment and realtime dosimetry modules for IPDT on the whole prostate glandular tissue. The method includes reconstruction of the target geometry, optimization of source fiber positions within this geometry, monitoring of the light attenuation during the treatment procedure and updating individual fiber irradiation times to take into account any variation in tissue light transmission. A control device that is arranged to restrict delivery of therapeutic light treatment at least temporary in dependence of at least one attribute of one of photodynamic treatment parameters. In comparison to no treatment feedback, a significant undertreatment of the patient as well as damage to healthy organs at risk are avoided.

    摘要翻译： 公开了一种用于控制和调节受试者中的间质性光动力光疗法（IPDT）中的光的方法和系统。 更具体地，使用用于在PDT处理期间确定组织状态的计算方法来描述用于控制间质肿瘤光动力光疗法中的光的方法。 该状态用于反馈回路以控制持续的PDT治疗。 公开了构成用于IPDT对整个前列腺腺组织的预处理和实时剂量测定模块的方法。 该方法包括重建目标几何形状，优化在该几何形状内的源光纤位置，监测处理过程中的光衰减和更新各个光纤照射时间以考虑到组织光透射中的任何变化。 一种控制装置，其被配置为根据光动力学治疗参数之一的至少一个属性至少临时地限制治疗性光处理的递送。 与没有治疗反馈相比，避免了对患者的重大治疗以及危及健康器官的损害。