CELL CULTURE MEMBER AND SURFACE MODIFICATION METHOD THEREFOR

    公开(公告)号:EP4269551A1

    公开(公告)日:2023-11-01

    申请号:EP21910974.1

    申请日:2021-12-23

    IPC分类号: C12M1/00 C12M3/00

    摘要: Provided are a cell culture member having excellent cell culture performance and its long-term stability, and a method for modifying the surface thereof. The cell culture member according to the present invention is a cell culture member having at least a holding region that holds an adherent cell and contains a polymer compound, wherein at least a part of the holding region is a surface-modified region in which a functional group containing a nitrogen atom is directly chemically bonded to a part of carbon atoms and/or silicon atoms constituting the polymer compound, and the present invention can provide a cell culture member that improves adhesiveness of the adherent cell to the surface-modified region, suppresses deterioration over time of adhesiveness, and is excellent in cell culture performance and its long-term stability.

    IMMOBILIZED PRODUCT AND METHOD FOR PRODUCING SAME

    公开(公告)号:EP3451349A1

    公开(公告)日:2019-03-06

    申请号:EP17789396.3

    申请日:2017-04-20

    摘要: To provide a novel immobilized product in which a carbon material and/or a silicon material is/are immobilized on a base material surface by a chemical bond via a linking group, and a method for producing the same. The immobilized product (10) of the present invention is an immobilized product in which a carbon material (11) is immobilizing on a surface of a base material (12), wherein the carbon material (11) is chemically bonded on the surface of the base material (12) via a linking group, and the linking group is at least any one selected from the group consisting of a -NH group, a -NH-R 1 -NH group, a -SO group, a R 2 group, an -O-R 3 -O group, and a R 4 group (in which the R 1 to R 4 each independently represent at least one selected from the group consisting of a chain alkyl group, a cyclic alkyl group, a chain alkenyl group, a cyclic alkenyl group, a chain alkynyl group, an aryl group, and functional groups in which at least one of a hydroxyl group, a halogen, an ester group, an ether group, a carbonyl group, an amino group, an amide group, a cyano group, a thiol group, a thioester group, or a thioether group is further bonded to these functional groups).

    CELL CULTURING MEMBER, AND METHOD FOR MODIFYING SURFACE THEREOF

    公开(公告)号:EP4269559A1

    公开(公告)日:2023-11-01

    申请号:EP21910939.4

    申请日:2021-12-23

    IPC分类号: C12M3/00 C08J7/12

    摘要: Provided are a cell culture member having excellent cell culture performance and its long-term stability, and a method for modifying the surface thereof. The cell culture member according to the present invention is a cell culture member having at least a holding region that holds an adherent cell and contains a polymer compound, wherein at least a part of the holding region is a surface-modified region in which a fluorine atom is directly chemically bonded to a part of carbon atoms and/or silicon atoms constituting the polymer compound, and the present invention can provide a cell culture member that improves adhesiveness of the adherent cell to the surface-modified region, suppresses deterioration over time of adhesiveness, and is excellent in cell culture performance and its long-term stability.