KOI HERPES VIRUS-SPECIFIC ANTIBODY AND ANTIGEN THEREOF
    5.
    发明公开
    KOI HERPES VIRUS-SPECIFIC ANTIBODY AND ANTIGEN THEREOF 审中-公开
    抗生素DARAUS的KOI-HERPESVIRUS-SPEZIFISCHERANTIKÖRPER

    公开(公告)号:EP2412721A1

    公开(公告)日:2012-02-01

    申请号:EP10755676.3

    申请日:2010-03-25

    摘要: The present invention provides: a koi herpes virus-specific antigenic peptide that reacts with an anti-koi herpes virus antibody but does not react with an anti-cyprinid herpes virus-1. antibody; an anti-koi herpes virus-specific antibody that is specific for koi herpes virus and does not exhibit cross-reactivity with cyprinid herpes virus-1; and a test or detection kit using the koi herpes virus-specific antigen or the anti-koi herpes virus-specific antibody. A region useful as the major antigen of koi herpes virus (KHV) was found from the koi herpes virus genomic DNA. Moreover, it was confirmed that an antibody directed against this region as an antigen has high detection sensitivity for koi herpes virus (KHV) without exhibiting cross-reactivity with cyprinid herpes virus-1 (CHV).

    摘要翻译: 本发明提供:与抗猕猴病毒抗体反应但不与抗鲤科疱疹病毒-1反应的锦鲤疱疹病毒特异性抗原肽。 抗体; 一种抗锦鲤疱疹病毒特异性抗体,其对锦鲤疱疹病毒具有特异性,并且不显示与鲤科疱疹病毒-1的交叉反应性; 以及使用锦鲤疱疹病毒特异性抗原或抗 - 锦鲤疱疹病毒特异性抗体的测试或检测试剂盒。 从锦鲤疱疹病毒基因组DNA中发现可用作锦鲤疱疹病毒(KHV)的主要抗原的区域。 此外,证实针对该区域作为抗原的抗体对于锦鲤疱疹病毒(KHV)没有显示与鲤科疱疹病毒-1(CHV)的交叉反应性的高检测灵敏度。