公开(公告)号：EP1541575A1

公开(公告)日：2005-06-15

申请号：EP03771268.4

申请日：2003-07-16

申请人： Sumitomo Chemical Takeda Agro Company, Limited

发明人： TABUCHI, Takanori ,  YAMAMOTO, Tetsuhiro ,  KAJIWARA, Takeshi B-1103, Shitinakandatsu,

IPC分类号： C07D487/04

CPC分类号： A01N47/36 ,  C07D487/04

摘要： A process for easily and inexpensively producing an imidazo[1,2-b]pyridazin-3-ylsulfonamide derivative which has a substituent bonded to the 6-position carbon atom and is represented by the formula (II):
(wherein R represents lower alkyl, lower cycloalkyl optionally substituted by lower alkyl, lower alkenyl, or lower alkynyl), the process comprising reacting an imidazo[1,2-b]pyridazine compound represented by the formula (I):
(wherein X represents halogeno or lower alkyl optionally substituted by halogeno; Y represents hydrogen or SO 2 N=CH-NR 1 R 2 ; and Z represents halogeno or OSO 2 R 3 ) with an organometallic compound in the presence of a transition metal catalyst. The derivative is useful as an intermediate for herbicides.

摘要翻译： 具有与6-位碳原子键合的取代基并由式（II）表示的咪唑并[1,2-b]哒嗪-3-基磺酰胺衍生物的方法：其中R表示低级烷基， 低级烷基，低级烯基或低级炔基取代的低级环烷基），该方法包括使由式（I）表示的咪唑并[1,2-b]哒嗪化合物：其中X表示任选被卤素取代的卤代或低级烷基 ; Y表示氢或SO 2 N = CH-NR 1 R 2; Z表示卤代或OSO 2 R 3）与有机金属化合物在过渡金属催化剂存在下反应。 该衍生物可用作除草剂的中间体。