NOVEL PROCESS FOR PRODUCING IMIDAZO(1,2-B)PYRIDAZINE DERIVATIVE
    1.
    发明公开
    NOVEL PROCESS FOR PRODUCING IMIDAZO(1,2-B)PYRIDAZINE DERIVATIVE 有权
    维生素VERFAHREN ZUR HERSTELLUNG EINES IMIDAZO(1,2-B)PYRIDAZINDERIVATS

    公开(公告)号:EP1541575A1

    公开(公告)日:2005-06-15

    申请号:EP03771268.4

    申请日:2003-07-16

    IPC分类号: C07D487/04

    CPC分类号: A01N47/36 C07D487/04

    摘要: A process for easily and inexpensively producing an imidazo[1,2-b]pyridazin-3-ylsulfonamide derivative which has a substituent bonded to the 6-position carbon atom and is represented by the formula (II):
    (wherein R represents lower alkyl, lower cycloalkyl optionally substituted by lower alkyl, lower alkenyl, or lower alkynyl), the process comprising reacting an imidazo[1,2-b]pyridazine compound represented by the formula (I):
    (wherein X represents halogeno or lower alkyl optionally substituted by halogeno; Y represents hydrogen or SO 2 N=CH-NR 1 R 2 ; and Z represents halogeno or OSO 2 R 3 ) with an organometallic compound in the presence of a transition metal catalyst. The derivative is useful as an intermediate for herbicides.

    摘要翻译: 具有与6-位碳原子键合的取代基并由式(II)表示的咪唑并[1,2-b]哒嗪-3-基磺酰胺衍生物的方法:其中R表示低级烷基, 低级烷基,低级烯基或低级炔基取代的低级环烷基),该方法包括使由式(I)表示的咪唑并[1,2-b]哒嗪化合物:其中X表示任选被卤素取代的卤代或低级烷基 ; Y表示氢或SO 2 N = CH-NR 1 R 2; Z表示卤代或OSO 2 R 3)与有机金属化合物在过渡金属催化剂存在下反应。 该衍生物可用作除草剂的中间体。