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1.发明授权
公开(公告)号：EP3080103B9
公开(公告)日：2018-09-19
申请号：EP14825001.2
申请日：2014-12-11
发明人： HOPKINS, Brian, T. , MA, Bin , CHAN, Timothy, Raymond , SUN, Lihong , ZHANG, Lei , KUMARAVEL, Gnanasambandam , LYSSIKATOS, Joseph, P. , KOCH, Kevin , MIAO, Hua
IPC分类号： C07D403/12 , C07D401/14 , C07D413/14 , C07D409/14 , C07D417/12 , C07D417/14 , C07D495/04 , C07D513/04 , A61K31/44 , A61K31/505 , A61K31/506 , A61P25/02 , A61P35/00 , A61P37/00
CPC分类号： C07D403/12 , A61K31/506 , C07D239/30 , C07D401/14 , C07D409/14 , C07D413/14 , C07D417/12 , C07D417/14 , C07D487/04 , C07D495/04 , C07D513/04 , C07F5/027
摘要： The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
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2.发明公开
公开(公告)号：EP3357921A2
公开(公告)日：2018-08-08
申请号：EP18160575.9
申请日：2014-12-11
发明人： HOPKINS, Brian T. , MA, Bin , CHAN, Timothy, Raymond , SUN, Lihong , ZHANG, Lei , KUMARAVEL, Gnanasambandam , LYSSIKATOS, Joseph, P. , KOCH, Kevin , MIAO, Hua
IPC分类号： C07D403/12 , C07D401/14 , C07D413/14 , C07D409/14 , C07D417/12 , C07D417/14 , C07D495/04 , C07D513/04 , A61K31/44 , A61K31/505 , A61K31/506 , A61P25/02 , A61P35/00 , A61P37/00 , C07D239/30 , C07F5/02
CPC分类号： C07D403/12 , A61K31/506 , C07D239/30 , C07D401/14 , C07D409/14 , C07D413/14 , C07D417/12 , C07D417/14 , C07D487/04 , C07D495/04 , C07D513/04 , C07F5/027
摘要： The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
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3.发明公开
公开(公告)号：EP3357921A3
公开(公告)日：2018-09-12
申请号：EP18160575.9
申请日：2014-12-11
发明人： HOPKINS, Brian T. , MA, Bin , CHAN, Timothy, Raymond , SUN, Lihong , ZHANG, Lei , KUMARAVEL, Gnanasambandam , LYSSIKATOS, Joseph, P. , KOCH, Kevin , MIAO, Hua
IPC分类号： C07D403/12 , C07D401/14 , C07D413/14 , C07D409/14 , C07D417/12 , C07D417/14 , C07D495/04 , C07D513/04 , A61K31/44 , A61K31/505 , A61K31/506 , A61P25/02 , A61P35/00 , A61P37/00 , C07D239/30 , C07F5/02
CPC分类号： C07D403/12 , A61K31/506 , C07D239/30 , C07D401/14 , C07D409/14 , C07D413/14 , C07D417/12 , C07D417/14 , C07D487/04 , C07D495/04 , C07D513/04 , C07F5/027
摘要： The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
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4.发明授权BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY 有权用于治疗肿瘤，神经学和免疫学中的人类疾病的双芳基化合物
公开(公告)号：EP3080103B1
公开(公告)日：2018-04-18
申请号：EP14825001.2
申请日：2014-12-11
发明人： HOPKINS, Brian, T. , MA, Bin , CHAN, Timothy, Raymond , SUN, Lihong , ZHANG, Lei , KUMARAVEL, Gnanasambandam , LYSSIKATOS, Joseph, P. , KOCH, Kevin , MIAO, Hua
IPC分类号： C07D403/12 , C07D401/14 , C07D413/14 , C07D409/14 , C07D417/12 , C07D417/14 , C07D495/04 , C07D513/04 , A61K31/44 , A61K31/505 , A61K31/506 , A61P25/02 , A61P35/00 , A61P37/00
CPC分类号： C07D403/12 , A61K31/506 , C07D239/30 , C07D401/14 , C07D409/14 , C07D413/14 , C07D417/12 , C07D417/14 , C07D487/04 , C07D495/04 , C07D513/04 , C07F5/027
摘要： The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
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5.发明公开BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY 有权用于治疗肿瘤，神经学和免疫学中的人类疾病的双芳基化合物
公开(公告)号：EP3080103A1
公开(公告)日：2016-10-19
申请号：EP14825001.2
申请日：2014-12-11
发明人： HOPKINS, Brian, T. , MA, Bin , CHAN, Timothy, Raymond , SUN, Lihong , ZHANG, Lei , KUMARAVEL, Gnanasambandam , LYSSIKATOS, Joseph, P. , KOCH, Kevin , MIAO, Hua
IPC分类号： C07D403/12 , C07D401/14 , C07D413/14 , C07D409/14 , C07D417/12 , C07D417/14 , C07D495/04 , C07D513/04 , A61K31/44 , A61K31/505 , A61K31/506 , A61P25/02 , A61P35/00 , A61P37/00
CPC分类号： C07D403/12 , A61K31/506 , C07D239/30 , C07D401/14 , C07D409/14 , C07D413/14 , C07D417/12 , C07D417/14 , C07D487/04 , C07D495/04 , C07D513/04 , C07F5/027
摘要： The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
摘要翻译： 本发明提供了可用作布鲁顿酪氨酸激酶抑制剂并表现出其所需特性的化合物及其组合物。
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公开(公告)号：EP3872075A1
公开(公告)日：2021-09-01
申请号：EP21168048.3
申请日：2014-12-11
申请人： Biogen MA Inc.
发明人： HOPKINS, Brian T , MA, Bin , CHAN, Timothy, Raymond , SUN, Lihong , ZHANG, Lei , KUMARAVEL, Gnanasambandam , LYSSIKATOS, Joseph, P , KOCH, Kevin , MIAO, Hua
IPC分类号： C07D403/12 , C07D401/14 , C07D413/14 , C07D409/14 , C07D417/12 , C07D417/14 , C07D495/04 , C07D513/04 , A61K31/44 , A61K31/505 , A61K31/506 , A61P25/02 , A61P35/00 , A61P37/00 , C07D239/30 , C07F5/02
摘要： The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
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