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公开(公告)号:EP3980080A1
公开(公告)日:2022-04-13
申请号:EP20751359.9
申请日:2020-06-10
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公开(公告)号:EP2989239A2
公开(公告)日:2016-03-02
申请号:EP14788445.6
申请日:2014-04-23
CPC分类号: G01N33/6857 , C07K16/00 , C07K16/3007 , C07K16/32 , C07K2317/14 , C07K2317/24 , C07K2317/55 , C07K2317/92
摘要: The invention relates to a method for generating and selecting Fab fragments using ribosomal display and cell-free protein synthesis. The invention also provides a ribosomal display reaction system for generating Fab fragment complexes. The compositions of a Fab fragment complex and a library thereof are also provided.
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公开(公告)号:EP3962951A1
公开(公告)日:2022-03-09
申请号:EP20729887.8
申请日:2020-05-01
发明人: LEE, John , STAFFORD, Ryan , YAM, Alice , LI, Xiaofan , YU, Abigail , GAKHAL, Amandeep , ARMSTRONG, Stephanie
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公开(公告)号:EP3684814A1
公开(公告)日:2020-07-29
申请号:EP18782283.8
申请日:2018-09-17
发明人: STAFFORD, Ryan , YAM, Alice , LI, Xiaofan , YIN, Gang , KLINE, Toni , ABRAHAMS, Cristina , DE ALMEIDA, Venita
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公开(公告)号:EP2989239B1
公开(公告)日:2018-07-04
申请号:EP14788445.6
申请日:2014-04-23
CPC分类号: G01N33/6857 , C07K16/00 , C07K16/3007 , C07K16/32 , C07K2317/14 , C07K2317/24 , C07K2317/55 , C07K2317/92
摘要: The invention relates to a method for generating and selecting Fab fragments using ribosomal display and cell-free protein synthesis. The invention also provides a ribosomal display reaction system for generating Fab fragment complexes. The compositions of a Fab fragment complex and a library thereof are also provided.
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公开(公告)号:EP3774901A1
公开(公告)日:2021-02-17
申请号:EP19716652.3
申请日:2019-03-25
发明人: YAM, Alice , STAFFORD, Ryan , LI, Xiaofan , YANG, Junhao , ARMSTRONG, Stephanie , YU, Abigail
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8.
公开(公告)号:EP3708227A1
公开(公告)日:2020-09-16
申请号:EP19196549.0
申请日:2015-07-20
发明人: PENTA, Kalyani , STAFFORD, Ryan , GILL, Avinash , LI, Xiafon , YAM, Alice , THANOS, Christopher , SATO, Aaron
摘要: Provided herein are antibodies that selectively bind to CD74 and its isoforms and homologs, and compositions comprising the antibodies. Also provided are methods of using the antibodies, such as therapeutic and diagnostic methods.
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公开(公告)号:EP3584255A1
公开(公告)日:2019-12-25
申请号:EP19168498.4
申请日:2013-08-30
IPC分类号: C07K14/535 , C07C247/00 , C07K14/00
摘要: Provided herein are modified amino acids comprising an azido group, polypeptides, antibodies and conjugates comprising the modified amino acids, and methods of producing the polypeptides, antibodies and conjugates comprising the modified amino acids. The polypeptides, antibodies and conjugates are useful in methods of treatment and prevention, methods of detection and methods of diagnosis.
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10.
公开(公告)号:EP3377533A2
公开(公告)日:2018-09-26
申请号:EP16805701.6
申请日:2016-11-18
发明人: STAFFORD, Ryan , YAM, Alice , LEE, John , SATO, Aaron
IPC分类号: C07K16/28
CPC分类号: C07K16/2803 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/55 , C07K2317/622 , C07K2317/76 , C07K2317/92
摘要: Provided herein are antibodies that selectively bind to LAG3 and its isoforms and homologs, and compositions comprising the antibodies. Also provided are methods of using the antibodies, such as therapeutic and diagnostic methods.
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