专利检索 ap:("Synta Pharmaceuticals Corp.") AND inv:"FRIEDLAND, Julie" 第 1 页

1.

发明公开
COMBINATION THERAPY OF HSP90 INHIBITORY COMPOUNDS WITH PROTEASOME INHIBITORS 审中-公开
标题翻译： HSP90发炎化合物和蛋白酶体抑制剂联合治疗

公开(公告)号：EP2663305A1

公开(公告)日：2013-11-20

申请号：EP12700765.6

申请日：2012-01-10

申请人： Synta Pharmaceuticals Corp.

发明人： PROIA, David , FRIEDLAND, Julie

IPC分类号： A61K31/4196 , A61K31/5377 , A61K31/675 , A61K45/06 , A61P35/00

CPC分类号： A61K31/4196 , A61K31/5377 , A61K31/675 , A61K31/69 , A61K45/06 , A61K2300/00

摘要： A composition comprising a proteasome inhibitor, and an Hsp90 inhibitor according to the following formulae (I) or (Ia), a tautomer, or a pharmaceutically acceptable salt thereof, wherein the variables in the structural formulae are defined herein. Also provided are methods for treating a proliferative disorder such as cancer in a subject in need thereof, using pharmaceutical combinations described herein.