公开(公告)号：EP2572674A3

公开(公告)日：2013-08-07

申请号：EP12185964.9

申请日：2002-07-08

申请人： Syntach AG

发明人： van Tassel, Robert ,  Schwartz, Robert ,  Holmes, David

IPC分类号： A61F2/06 ,  A61F2/24 ,  A61F2/82 ,  A61F2/07

CPC分类号： A61M29/02 ,  A61F2/07 ,  A61F2/24 ,  A61F2/2481 ,  A61F2/2487 ,  A61F2/82 ,  A61F2/848 ,  A61F2/90 ,  A61F2002/821 ,  A61F2002/8483 ,  A61F2220/0016 ,  A61M29/00

摘要： A device (30) for modifying conduction, electrical connection and propagation properties in a tissue comprising :a structural platform (30) made of a biocompatible material;
the platform (30) conformable to a shape of a target tissue site (36) having a vessel wall; the platform (30) having a treatment component sized and shaped to induce a fibrotic response in the target tissue (36); and the treatment component being configured to cause sufficient fibrotic response so as to substantially eliminate the cardiac arrhythmias, wherein the device is configured to be radially expanded to overstretch the vessel wall so that the overstretching induce fibrosis in the tissue at the target tissue site (36).

公开(公告)号：EP2572674A2

公开(公告)日：2013-03-27

申请号：EP12185964.9

申请日：2002-07-08

申请人： Syntach AG

发明人： van Tassel, Robert ,  Schwartz, Robert ,  Holmes, David

IPC分类号： A61F2/06 ,  A61F2/24

CPC分类号： A61M29/02 ,  A61F2/07 ,  A61F2/24 ,  A61F2/2481 ,  A61F2/2487 ,  A61F2/82 ,  A61F2/848 ,  A61F2/90 ,  A61F2002/821 ,  A61F2002/8483 ,  A61F2220/0016 ,  A61M29/00

摘要： A device (30) for modifying conduction, electrical connection and propagation properties in a tissue comprising :a structural platform (30) made of a biocompatible material;
the platform (30) conformable to a shape of a target tissue site (36) having a vessel wall; the platform (30) having a treatment component sized and shaped to induce a fibrotic response in the target tissue (36); and the treatment component being configured to cause sufficient fibrotic response so as to substantially eliminate the cardiac arrhythmias, wherein the device is configured to be radially expanded to overstretch the vessel wall so that the overstretching induce fibrosis in the tissue at the target tissue site (36).

摘要翻译： 一种用于改变组织中的传导，电连接和传播特性的装置（30），包括：由生物相容性材料制成的结构平台（30） 所述平台（30）适应于具有血管壁的目标组织部位（36）的形状; 所述平台（30）具有处理部件，所述处理部件的尺寸和形状被设计成在所述目标组织（36）中诱导纤维化应答; 并且所述治疗部件被配置为引起足够的纤维化反应以基本上消除心律失常，其中所述装置被配置为径向扩张以使血管壁过度延伸，使得所述过度扩张诱​​导所述目标组织部位处的组织中的纤维化（36 ）。