公开(公告)号：EP2889620A1

公开(公告)日：2015-07-01

申请号：EP14198316.3

申请日：2009-04-28

申请人： Sysmex Corporation

发明人： Matsumoto, Hideaki ,  Uchihashi, Kinya ,  Itose, Yuji ,  Konishi, Aya ,  Yoshida, Ayumu

IPC分类号： G01N33/48 ,  G01N33/49 ,  G01N33/72

CPC分类号： C12Q1/68 ,  G01N33/5094 ,  G01N33/56905 ,  G01N2333/44 ,  Y02A50/58

摘要： This blood analyzer includes a sample preparation portion preparing a first measurement sample containing a blood sample and a hemolytic agent and a second measurement sample containing the blood sample, the same hemolytic agent as the hemolytic agent and a staining agent and a control portion classifying white blood cells in the first measurement sample into at least four groups of monocytes, neutrophils, eosinophils and a group of the others on the basis of fluorescent information and two types of scattered light information generated by a light information generation portion and classifying blood cells in the second measurement sample into malaria-infected red blood cells and a group of the others on the basis of fluorescent information and scattered light information generated by the light information generation portion. Different dilution magnifications of the hemolytic agent as regards first and second sample are present in product and method to achieve the differentiation between malaria infected red blood cells and different types of white blood cells and count the infected cells

摘要翻译： 该血液分析装置包括制备含有血液试样和溶血剂的第一测定试样的试样调制部和含有血液试样的第二测定试样，与溶血剂相同的溶血剂和染色剂，以及将白血球分类的对照部 基于荧光信息和由光信息产生部生成的两种类型的散射光信息将第一测量样品中的细胞分成至少四组单核细胞，嗜中性粒细胞，嗜酸性粒细胞和其他组，并在第二组中对血细胞进行分类 基于由光信息生成部生成的荧光信息和散射光信息，将测定样品分配到疟疾感染的红细胞和其他组中。 在产品和方法中存在关于第一和第二样品的溶血剂的不同稀释倍率，以实现疟疾感染的红细胞和不同类型的白细胞之间的分化并计数感染的细胞

公开(公告)号：EP0806664B1

公开(公告)日：2005-06-22

申请号：EP97610010.7

申请日：1997-04-10

申请人： Sysmex Corporation

发明人： Akai, Yasumasa ,  Hatanaka, Kayo ,  Itose, Yuji ,  Sakata, Takashi

IPC分类号： G01N33/49 ,  G01N33/50 ,  G01N33/80 ,  G01N15/10 ,  G01N1/30

CPC分类号： G01N33/5094 ,  G01N15/1459 ,  G01N2015/1006 ,  G01N2015/1402 ,  Y10S436/80 ,  Y10T436/10 ,  Y10T436/101666

公开(公告)号：EP2275205B1

公开(公告)日：2019-03-20

申请号：EP10169500.5

申请日：2010-07-14

申请人： SYSMEX CORPORATION

发明人： Ueda, Sachiko ,  Mori, Yusuke ,  Ohashi, Hiroyuki ,  Itose, Yuji ,  Uchihashi, Kinya ,  Nakamura, Yoichi ,  Sugitani, Kohei

IPC分类号： B01L3/00 ,  B01L9/00 ,  G01N35/10 ,  B01L3/02

公开(公告)号：EP2275205A2

公开(公告)日：2011-01-19

申请号：EP10169500.5

申请日：2010-07-14

申请人： SYSMEX CORPORATION

发明人： Ueda, Sachiko ,  Mori, Yusuke ,  Ohashi, Hiroyuki ,  Itose, Yuji ,  Uchihashi, Kinya ,  Nakamura, Yoichi ,  Sugitani, Kohei

IPC分类号： B01L3/00

CPC分类号： B01L3/0293 ,  B01L3/527 ,  B01L9/00 ,  B01L2200/185 ,  B01L2300/021 ,  G01N35/1002

摘要： A reagent container set is disclosed which comprises:
a first reagent container for accommodating a first reagent to be used in a sample analyzer, the top part of the first reagent container having a first aspiration opening for inserting a first reagent aspirating tube to aspirate the first reagent;
a waste fluid container for accommodating the first reagent used in the sample analyzer as a waste fluid, the top of the waste fluid container having a discharge opening for inserting a waste fluid discharging tube to discharge the waste fluid into the waste fluid container;
a box for accommodating the first reagent container and the waste fluid container; and
a container holding member for holding the first reagent container and the waste fluid container so that the first aspiration opening and the discharge opening are disposed at predetermined positions, the container holding member being maintained at a predetermined position within the box.

摘要翻译： 公开了一种试剂容器组，其包括：第一试剂容器，其用于容纳用于样本分析仪的第一试剂，第一试剂容器的顶部具有用于插入第一试剂吸管的第一抽吸开口，以吸取第一试剂吸入管 试剂; 废液容器，其用于容纳作为废液的样品分析仪中使用的第一试剂，废液容器的顶部具有用于插入废液排放管以将废液排放到废液容器中的排放开口; 容纳第一试剂容器和废液容器的盒子; 以及容器保持部件，用于保持所述第一试剂容器和所述废液容器，使得所述第一抽吸开口和所述排出口设置在预定位置处，所述容器保持部件保持在所述箱内的预定位置处。

公开(公告)号：EP2275205A3

公开(公告)日：2017-11-15

申请号：EP10169500.5

申请日：2010-07-14

申请人： SYSMEX CORPORATION

发明人： Ueda, Sachiko ,  Mori, Yusuke ,  Ohashi, Hiroyuki ,  Itose, Yuji ,  Uchihashi, Kinya ,  Nakamura, Yoichi ,  Sugitani, Kohei

IPC分类号： B01L3/00 ,  B01L9/00 ,  G01N35/10 ,  B01L3/02

CPC分类号： B01L3/0293 ,  B01L3/527 ,  B01L9/00 ,  B01L2200/185 ,  B01L2300/021 ,  G01N35/1002

摘要： A reagent container set is disclosed which comprises:
a first reagent container for accommodating a first reagent to be used in a sample analyzer, the top part of the first reagent container having a first aspiration opening for inserting a first reagent aspirating tube to aspirate the first reagent;
a waste fluid container for accommodating the first reagent used in the sample analyzer as a waste fluid, the top of the waste fluid container having a discharge opening for inserting a waste fluid discharging tube to discharge the waste fluid into the waste fluid container;
a box for accommodating the first reagent container and the waste fluid container; and
a container holding member for holding the first reagent container and the waste fluid container so that the first aspiration opening and the discharge opening are disposed at predetermined positions, the container holding member being maintained at a predetermined position within the box.

公开(公告)号：EP2889620B1

公开(公告)日：2017-10-11

申请号：EP14198316.3

申请日：2009-04-28

申请人： Sysmex Corporation

发明人： Matsumoto, Hideaki ,  Uchihashi, Kinya ,  Itose, Yuji ,  Konishi, Aya ,  Yoshida, Ayumu

IPC分类号： G01N33/50 ,  G01N33/569

CPC分类号： C12Q1/68 ,  G01N33/5094 ,  G01N33/56905 ,  G01N2333/44 ,  Y02A50/58

摘要： This blood analyzer includes a sample preparation portion preparing a first measurement sample containing a blood sample and a hemolytic agent and a second measurement sample containing the blood sample, the same hemolytic agent as the hemolytic agent and a staining agent and a control portion classifying white blood cells in the first measurement sample into at least four groups of monocytes, neutrophils, eosinophils and a group of the others on the basis of fluorescent information and two types of scattered light information generated by a light information generation portion and classifying blood cells in the second measurement sample into malaria-infected red blood cells and a group of the others on the basis of fluorescent information and scattered light information generated by the light information generation portion.

公开(公告)号：EP1715345B1

公开(公告)日：2013-12-04

申请号：EP06006120.7

申请日：2006-03-24

申请人： SYSMEX CORPORATION

发明人： Yoshida, Ayumu ,  Uchihashi, Kinya ,  Itose, Yuji ,  Konishi, Aya ,  Iizuka, Hiromitsu

IPC分类号： G01N33/569 ,  G01N33/80

CPC分类号： G01N33/80 ,  G01N33/56905 ,  Y02A50/58

摘要： A reagent for partially lysing a cell membrane of a red blood cell infected with a malaria parasite, comprising: a first surfactant which has predetermined lysing ability for the red blood cell membrane; and a second surfactant which has weaker lysing ability than that of the first surfactant; wherein the reagent has pH of 5 to 7 and osmotic pressure of 200 to 300 mOsm/kg·H 2 O; and wherein the reagent partially lyses the malaria infected red blood cell membrane such that a malaria parasite is retained in the red blood cell and fluorescent dye passes through the cell membrane, is disclosed. A reagent for detecting malaria infected red blood cells, and a sample analyzing method for detecting malaria infected red blood cells, are also disclosed.