公开(公告)号：EP1970076A1

公开(公告)日：2008-09-17

申请号：EP06843226.9

申请日：2006-12-26

申请人： TEIKOKU SEIYAKU CO., LTD. ,  NIHON NOHYAKU CO., LTD.

发明人： ISHIMA, Tomohiro ,  NARUSE, Mamoru ,  KANEDA, Hideo ,  KANAI, Kazuo ,  SEKINE, Takashi ,  OOTA, Shinichi ,  YOSHIMURA, Tomonari

IPC分类号： A61K47/22 ,  A61K9/70 ,  A61K31/4178 ,  A61K45/00 ,  A61K47/10 ,  A61K47/32 ,  A61K47/34 ,  A61K47/36 ,  A61K47/38 ,  A61K47/42 ,  A61P17/00 ,  A61P31/10

CPC分类号： A61K9/7061 ,  A61F13/02 ,  A61F13/105 ,  A61F2013/00906 ,  A61K9/0014 ,  A61K31/00 ,  A61K31/4174 ,  A61K31/4178 ,  A61K45/06 ,  A61K47/10 ,  A61K47/22 ,  A61K47/32 ,  A61K47/38 ,  A61M35/00

摘要： Since treatment effects of conventional external preparations were not satisfactory, it is aimed to provide a novel external preparation that is excellent in drug permeability to nail, capable of fully exhibiting effects of an antifungal drug, and effective for treatments of diseases such as nail mycosis and nail candidiasis, particularly, treatments for nail tinea. The external preparation of this invention is a pharmaceutical composition for nail characterized by containing an antifungal drug, alkylpyrrolidone or a derivative thereof, and a crosslinking hydrogel.

摘要翻译： 由于常规外用制剂的治疗效果不能令人满意，目的在于提供一种能够充分发挥抗真菌药物效果的指甲药物渗透性优异的新型外用制剂，对于治疗诸如甲型真菌病等疾病有效。 指甲念珠菌病，特别是指甲癣的治疗。 本发明的外用制剂是用于指甲的药物组合物，其特征在于含有抗真菌药，烷基吡咯烷酮或其衍生物和交联水凝胶。