公开(公告)号：EP0967273B1

公开(公告)日：2005-12-21

申请号：EP99401562.6

申请日：1999-06-23

申请人： TERUMO KABUSHIKI KAISHA

发明人： Kimura, Tetsuhiro ,  Tokunaga, Norifumi ,  Omura, Yoshitaka

IPC分类号： C12N15/06

CPC分类号： C12M25/14 ,  A61K35/12 ,  C12N5/0068 ,  C12N5/0671 ,  C12N2533/30 ,  C12N2533/78

公开(公告)号：EP0967273A1

公开(公告)日：1999-12-29

申请号：EP99401562.6

申请日：1999-06-23

申请人： TERUMO KABUSHIKI KAISHA

发明人： Kimura, Tetsuhiro ,  Tokunaga, Norifumi ,  Omura, Yoshitaka

IPC分类号： C12N15/06

CPC分类号： C12M25/14 ,  A61K35/12 ,  C12N5/0068 ,  C12N5/0671 ,  C12N2533/30 ,  C12N2533/78

摘要： A cell supporting matrix which enables the cells to be supported at a high efficiency and at a high density in a short period is provided. The cell supporting matrix comprises a cell supporting layer 7 for supporting the cells, and a skin layer 8. The cell supporting layer 7 has formed therein a plurality of large pores 5 having a larger pore size and a plurality of communicating pores 6 having a smaller pore size. The large pores 5 are in finger-like structure form and are distributed in the cell supporting matrix 4. The longitudinal axis of the large pores 5 extends substantially in the flow direction of the fluid passing through the cell supporting matrix 4. The large pores 5 do not extend through the cell supporting matrix 4. The communicating pores 6 are formed such that their pore size decreases from the surface to the interior of the cell supporting matrix 4. The pore size of the communicating pores 6 range from below to beyond the size of the cells to be supported on the matrix 4.

摘要翻译： 提供了能够在短时间内以高效率和高密度地支撑电池的电池支撑基体。 电池支撑基体包括用于支撑电池的电池支撑层7和表皮层8.电池支撑层7中形成有多个具有较大孔径的大孔5和多个具有较小孔径的连通孔6 孔径。 大孔5处于指状结构形式并分布在细胞支撑基体4中。大孔5的纵向轴线基本上沿流过细胞支撑基质4的流体的流动方向延伸。大孔5 不延伸通过电池支撑基体4.连通孔6形成为使得它们的孔径从电池支撑基体4的表面到内部减小。连通孔6的孔径从下到下超过尺寸 要支撑在矩阵4上的单元格。