公开(公告)号：EP0790061A1

公开(公告)日：1997-08-20

申请号：EP96928679.8

申请日：1996-08-28

申请人： TORAY INDUSTRIES, INC.

发明人： TERAO, Toshihiko ,  KANAYAMA, Naohiro Hamamatsuidaihandayamashukusha ,  NARUTO, Masanobu ,  KANEKO, Tatsuya

IPC分类号： A61K38/19 ,  A61K38/20 ,  A61K38/21

CPC分类号： A61K38/195 ,  A61K38/191 ,  A61K38/2006 ,  A61K38/2053 ,  A61K38/217

摘要： A fertility agent comprising as the active ingredient a leukocyte migration for (interleukin 8, monocyte chemotactic factor, etc.) or a leukocyte migration factor inducer (interleukin 1, tumor necrotizing factor, interferon γ, platelet-activating factor, endotoxin, etc.). The effects of this drug are based on the fact that a leukocyte migration factor or an inducer thereof is efficacious as a single substance in the promotion of both of the growth of an ovum and the implantation of fertilized ovum. It is broadly usable in various industrial fields as a remedy for human and animal infertility and for veterinary and zootechnical purposes of, for example, promoting the production of industrial animals and conserving rare animal species.

摘要翻译： 包含作为活性成分的白细胞迁移（白细胞介素8，单核细胞趋化因子等）或白细胞迁移因子诱导剂（白细胞介素1，肿瘤坏死因子，干扰素γ，血小板活化因子，内毒素等）的生育剂 。 该药物的作用是基于白细胞迁移因子或其诱导剂作为单一物质有效促进卵子生长和受精卵的植入的事实。 可广泛用于各种工业领域，作为人类和动物不育症以及兽医和动物技术用途的补救方法，例如促进工业动物的生产和保护稀有动物物种。

公开(公告)号：EP0867452A1

公开(公告)日：1998-09-30

申请号：EP97944127.6

申请日：1997-10-15

申请人： TORAY INDUSTRIES, INC.

发明人： TERAO, Toshihiko ,  KANAYAMA, Naohiro Hamamatsuidaihandayamashukusha ,  IDA, Nobutaka

IPC分类号： C08B37/08 ,  A61K31/725

CPC分类号： A61K31/728

摘要： A cervical ripening agent contains as an active ingredient hyaluronic acid and/or a hyaluronic acid derivative. The present invention discloses the cervical ripening action of hyaluronic acid and/or a hyaluronic acid derivative, and exhibits effectiveness as a medicine and application means for not only parturition and abortion treatment but also treatment related to artificial fertilization.