-
公开(公告)号：EP2022793B1
公开(公告)日：2014-06-04
申请号：EP07744040.2
申请日：2007-05-24
发明人： KIYOTO, Taro , ANDO, Junichi , TANAKA, Tadashi , TSUTSUI, Yasuhiro , YOKOTANI, Mai , NOGUCHI, Toshiya , USHIYAMA, Fumihito , URABE, Hiroki , HORIKIRI, Hiromasa
IPC分类号： C07D471/04 , A61K31/4375 , A61K31/4985 , A61K31/5365 , A61K31/542 , A61P31/04 , C07D519/00
CPC分类号： C07D471/04 , C07D491/056 , C07D519/00 , Y02P20/55
-
2.发明公开
公开(公告)号：EP2221309A1
公开(公告)日：2010-08-25
申请号：EP08855286.4
申请日：2008-11-25
发明人： KIYOTO, Taro , TAKEBAYASHI, Masahiro , BABA, Yasutaka , SYOJI, Muneo , NOGUCHI, Toshiya , USHIYAMA, Fumihito , URABE, Hiroki , HORIKIRI, Hiromasa
IPC分类号： C07D519/00 , A61K31/4545 , A61P31/04 , C07D309/40 , C07D491/056
CPC分类号： C07D519/00 , C07D309/40 , C07D491/04
摘要： Disclosed is 1-(2-(4-((2,3-dihydro(1,4)dioxino(2,3-c)pyridin-7-ylmethyl)amino)piperidin-1-yl)ethyl)-7-fluoro-1,5-naphthyridin-2(1H)-one monohydrate, which has strong antibacterial activity. The compound is highly safe and useful as an original drug for pharmaceutical preparations. Also disclosed is a method which is useful for producing 1-(2-(4-((2,3-dihydro(1,4)dioxino(2,3-c)pyridin-7-ylmethyl)amino)piperidin-1-yl)ethyl)-7-fluoro-1,5-naphthyridin-2(1H)-one monohydrate.
摘要翻译： 公开了1-（2-（4 - （（2,3-二氢（1,4）二氧杂环己烯（2,3-c）吡啶-7-基甲基）氨基）哌啶-1-基）乙基） -1,5-二氮杂萘-2（1H） - 酮一水合物，具有很强的抗菌活性。 该化合物作为药物制剂的原始药物是非常安全和有用的。 还公开了用于制备1-（2-（4 - （（2,3-二氢（1,4）二氧杂环己烯（2,3-c）吡啶-7-基甲基）氨基）哌啶-1-基） 乙基）-7-氟-1,5-二氮杂萘-2（1H） - 酮一水合物。
-
公开(公告)号：EP2221309B1
公开(公告)日：2013-07-24
申请号：EP08855286.4
申请日：2008-11-25
发明人： KIYOTO, Taro , TAKEBAYASHI, Masahiro , BABA, Yasutaka , SYOJI, Muneo , NOGUCHI, Toshiya , USHIYAMA, Fumihito , URABE, Hiroki , HORIKIRI, Hiromasa
IPC分类号： C07D519/00 , A61K31/4545 , A61P31/04 , C07D309/40 , C07D491/056 , C07D491/04
CPC分类号： C07D519/00 , C07D309/40 , C07D491/04
-
4.发明公开NOVEL HETEROCYCLIC COMPOUND OR SALT THEREOF AND INTERMEDIATE THEREOF 有权UE ON ON ON ON ON ON ON ON ON ON ON ON ON ON ON ON ON ON ON ON ON ON ON ON ON ON
公开(公告)号：EP2022793A1
公开(公告)日：2009-02-11
申请号：EP07744040.2
申请日：2007-05-24
发明人： KIYOTO, Taro , ANDO, Junichi , TANAKA, Tadashi , TSUTSUI, Yasuhiro , YOKOTANI, Mai , NOGUCHI, Toshiya , USHIYAMA, Fumihito , URABE, Hiroki , HORIKIRI, Hiromasa
IPC分类号： C07D471/04 , A61K31/4375 , A61K31/4985 , A61K31/5365 , A61K31/542 , A61P31/04 , C07D519/00
CPC分类号： C07D471/04 , C07D491/056 , C07D519/00 , Y02P20/55
摘要： Disclosed is a compound represented by the general formula: [wherein R 1 represents an aryl or heterocyclic group which may be substituted or the like; X 1 represents a C 2 -C 4 alkylene group or the like; X 2 , X 3 and X 5 independently represent NH, a bond or the like; X 4 represents a lower alkylene group, a bond or the like; Y 1 represents a bivalent alicyclic hydrocarbon residue which may be substituted or a bivalent alicyclic amine residue which may be substituted; and Z 1 , Z 2 , Z 3 , Z 4 , Z 5 and Z 6 independently represent a nitrogen atom, a group represented by the formula: CH, or the like, provided that at least one of Z 3 , Z 4 , Z 5 and Z 6 represents a nitrogen atom] or a salt thereof, which is useful as an antibacterial agent.
摘要翻译： 公开了由以下通式表示的化合物：其中R 1表示可被取代的芳基或杂环基等; X 1表示C 2〜C 4亚烷基等; X 2，X 3和X 5独立地表示NH，键等; X 4表示低级亚烷基，键等; Y 1表示可以被取代的二价脂环族烃残基或可以被取代的二价脂环族胺残基; Z 1，Z 2，Z 3，Z 4，Z 5和Z 6独立地表示氮原子，由式CH表示的基团等，条件是Z 3，Z 4，Z中的至少一个 5和Z 6表示氮原子]或其盐，其可用作抗菌剂。
-
-
-
搜索结果
4 条记录 (耗时 0.022 秒)
