-
1.发明授权COMPOSITION, METHOD AND KIT FOR POTENTIATING ANTITUMOR ACTIVITY AND FOR CURING TUMOR 失效组成，方法与仪器以强化抗肿瘤活性和肿瘤的治疗
公开(公告)号：EP0543015B1
公开(公告)日：1998-11-11
申请号：EP92910345.5
申请日：1992-05-22
发明人： SHIRASAKA, Tetsuhiko , FUKUSHIMA, Masakazu 9-7, Sencho 2-chome , OHSHIMO, Hideyuki 10-28, Minamimachi , SHIMAMOTO, Yuji 9-11, Ogino-sato 2-chome
IPC分类号： A61K31/53
CPC分类号： A61K31/53 , A61K31/44 , A61K31/70 , A61K31/505 , A61K2300/00
摘要： A composition for potentiating the antitumor activity of tegafur and reducing the adverse effects, comprising a compound represented by general formula (I) wherein X represents halogen or cyano and oxonic acid or a pharmaceutically acceptable salt thereof, and a method and kit therefor; and a composition for curing tumors comprising tegafur, a compound represented by formula (I) and oxonic acid or a pharmaceutically acceptable salt thereof; and a method and kit therefor.
-
2.发明授权OPTICALLY ACTIVE 1-PHENYLPYRROLIDONE DERIVATIVE AND PREPARATION THEREOF 失效光有源1-phenylpyrrolidone及其生产
公开(公告)号：EP0627419B1
公开(公告)日：1999-11-24
申请号：EP93919628.3
申请日：1993-09-08
发明人： YANO, Shingo 12-13-402, Naka-cho , OHNO, Tomoyasu 244-2-207, Haramachi , OGAWA, Kazuo 1446, Aza Takahata Aihata Ishii-cho , SHIRASAKA, Tetsuhiko
IPC分类号： C07D207/26
CPC分类号： C07D207/26
摘要： An optically active 1-phenylpyrrolidone derivative represented by general formula (I), wherein R represents an optically active α-phenylethylamino group which may be substituted; a 1-phenylpyrrolidone derivative represented by general formula (I-a), and a process for producing 1-phenylpyrrolidone derivatives represented by these formulae.
-
3.发明公开TEGAFUR-CONTAINING COMPOSITION FOR SINGLE DAILY AND ALTERNATE-DAY DOSING 审中-公开TEGAFURHALTIGE ZUSAMMENSETZUNG ZUR EINMALIGEN ODER MEHRMALIGENTÄGLICHENDOSIERUNG
公开(公告)号：EP2671590A1
公开(公告)日：2013-12-11
申请号：EP12741901.8
申请日：2012-01-30
IPC分类号： A61K31/513 , A61K31/4412 , A61K31/53 , A61P35/00 , A61P43/00
CPC分类号： A61K31/513 , A61K31/4412 , A61K31/53 , A61K2300/00
摘要： This invention provides an antitumor agent comprising a combination drug containing tegafur, gimeracil, and oteracil potassium, characterized by being repeatedly administered to a patient once a day every other day, four days a week, at a dose such that the tegafur is administered in an amount of 80 mg or more/dose when the patient has a body surface area of less than 1.25 m 2 , in an amount of 100 mg or more/dose when the patient has a body surface area of 1.25 to 1.5 m 2 , or in an amount of 120 mg or more/dose when the patient has a body surface area of not less than 1.5 m 2 .
摘要翻译： 本发明提供了一种抗肿瘤剂，其包含含有替加氟，吉美脯氨酸和奥特拉西钾的组合药物，其特征在于每隔一天，每周四天一天一次地向患者重复施用，剂量使得替加氟以 当患者体表面积小于1.25m 2时，当患者体表面积为1.25至1.5m 2时，其量为100mg或更多/剂量，或者在 当患者的体表面积不小于1.5m 2时，其量为120mg以上/剂量。
-
4.发明公开OPTICALLY ACTIVE 1-PHENYLPYRROLIDONE DERIVATIVE, INTERMEDIATE FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING BOTH 失效光有源1-phenylpyrrolidone，制造及其生产中间体，其旗下。
公开(公告)号：EP0627419A1
公开(公告)日：1994-12-07
申请号：EP93919628.3
申请日：1993-09-08
发明人： YANO, Shingo 12-13-402, Naka-cho , OHNO, Tomoyasu 244-2-207, Haramachi , OGAWA, Kazuo 1446, Aza Takahata Aihata Ishii-cho , SHIRASAKA, Tetsuhiko
IPC分类号： C07D207/26
CPC分类号： C07D207/26
摘要： An optically active 1-phenylpyrrolidone derivative represented by general formula (I), wherein R represents an optically active α-phenylethylamino group which may be substituted; a 1-phenylpyrrolidone derivative represented by general formula (I-a), and a process for producing 1-phenylpyrrolidone derivatives represented by these formulae.
摘要翻译： 光学活性的1- phenylpyrrolidone衍生物由通式（I）表示，worin光学活性的α-苯基乙氨基团可以被取代的 - [R darstellt; 由通式（I-A）表示的1- phenylpyrrolidone衍生物，以及用于制备由合成式餐饮代表1- phenylpyrrolidone衍生物的方法。
-
5.发明公开COMPOSITION, METHOD AND KIT FOR POTENTIATING ANTITUMOR ACTIVITY AND FOR CURING TUMOR 失效组成，方法与仪器以强化抗肿瘤活性和肿瘤的治疗。
公开(公告)号：EP0543015A1
公开(公告)日：1993-05-26
申请号：EP92910345.5
申请日：1992-05-22
发明人： SHIRASAKA, Tetsuhiko , FUKUSHIMA, Masakazu 9-7, Sencho 2-chome , OHSHIMO, Hideyuki 10-28, Minamimachi , SHIMAMOTO, Yuji 9-11, Ogino-sato 2-chome
IPC分类号： A61K31/53
CPC分类号： A61K31/53 , A61K31/44 , A61K31/70 , A61K31/505 , A61K2300/00
摘要： A composition for potentiating the antitumor activity of tegafur and reducing the adverse effects, comprising a compound represented by general formula (I) wherein X represents halogen or cyano and oxonic acid or a pharmaceutically acceptable salt thereof, and a method and kit therefor; and a composition for curing tumors comprising tegafur, a compound represented by formula (I) and oxonic acid or a pharmaceutically acceptable salt thereof; and a method and kit therefor.
摘要翻译： 甲用于增强替加氟的抗肿瘤活性和减少的不利影响，包括由通式（I）worin X darstellt卤素或氰基和氧嗪酸或其药学上可接受的盐，和一种方法及其试剂盒表示的化合物的组合物; 以及用于治疗肿瘤，包括替加氟，由式（I）和氧嗪酸或其药学上可接受的盐表示的化合物的组合物; 及其方法和试剂盒。
-
-
-
-
搜索结果
5 条记录 (耗时 0.012 秒)
