公开(公告)号：EP1080723A1

公开(公告)日：2001-03-07

申请号：EP99919525.8

申请日：1999-05-11

申请人： Takara Shuzo Co, Ltd.

发明人： TAKESAKO, Kazutoh ,  SAITO, Hideharu ,  KATO, Ikunoshin

IPC分类号： A61K31/16

CPC分类号： A61K31/16

摘要： The production of IgA is selectively inhibited by orally administering 15-deoxyspergualin or pharmacologically acceptable salts thereof, thus preventing and treating IgA-associated immunological diseases such as IgA nephropathy.

摘要翻译： 通过口服施用15-脱氧精胍菌素或其药理学上可接受的盐来选择性地抑制IgA的产生，从而预防和治疗IgA相关免疫疾病如IgA肾病。