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1.发明公开
公开(公告)号：EP0281822A2
公开(公告)日：1988-09-14
申请号：EP88102491.3
申请日：1988-02-20
CPC分类号： G01N33/6887 , A61K38/00 , C07K14/503 , C07K14/55 , C07K16/22 , C07K2319/00 , C07K2319/02 , C07K2319/75
摘要： A mutein of basic fibroblast growth factors (bFGF) possesses fibroblast growth promoting activity, growth stimulating activity of capillary endothelial cells and angiogenic activity, has high stability and is low toxicity. And therefore, the present mutein is advantageously used as a healing accelerator for burns etc., a therapeutic drug for thrombosis etc., and a cell cultivation promoter.
摘要翻译： 碱性成纤维细胞生长因子（bFGF）的突变蛋白具有成纤维细胞生长促进活性，毛细血管内皮细胞生长刺激活性和血管生成活性，具有高稳定性和低毒性。 因此，本发明的突变蛋白有利地用作燃烧等的愈合促进剂，血栓形成治疗药等，以及细胞培养促进剂。
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公开(公告)号：EP0281822B1
公开(公告)日：1994-07-20
申请号：EP88102491.3
申请日：1988-02-20
CPC分类号： G01N33/6887 , A61K38/00 , C07K14/503 , C07K14/55 , C07K16/22 , C07K2319/00 , C07K2319/02 , C07K2319/75
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公开(公告)号：EP0281822A3
公开(公告)日：1990-03-21
申请号：EP88102491.3
申请日：1988-02-20
CPC分类号： G01N33/6887 , A61K38/00 , C07K14/503 , C07K14/55 , C07K16/22 , C07K2319/00 , C07K2319/02 , C07K2319/75
摘要： A mutein of basic fibroblast growth factors (bFGF) possesses fibroblast growth promoting activity, growth stimulating activity of capillary endothelial cells and angiogenic activity, has high stability and is low toxicity. And therefore, the present mutein is advantageously used as a healing accelerator for burns etc., a therapeutic drug for thrombosis etc., and a cell cultivation promoter.
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