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    Smooth muscle mitogen and DNA coding therefor
    2.
    发明公开
    Smooth muscle mitogen and DNA coding therefor 失效
    丝丝霉素fuc die fat die glatte Muskulatur und dessen kodierende DNS。

    公开(公告)号：EP0555785A1

    公开(公告)日：1993-08-18

    申请号：EP93101871.7

    申请日：1993-02-06

    申请人： Takeda Chemical Industries, Ltd. ,  CHILDREN'S MEDICAL CENTER CORPORATION

    发明人： Folkmann, Moses Judah ,  Shing, Yuen ,  Igarashi, Koichi

    IPC分类号： C12N15/18 ,  C07K15/06

    CPC分类号： C07K14/475 ,  A61K38/00

    摘要： A recombinant non-glycosylated mammalian growth factor (BTC-GF) stimulates proliferation of human smooth muscle cells. Especially, the amino acid sequence of the protein deduced from the nucleotide sequence coding for human BTC-GF is as that comprising the amino acids No. 1 to No. 147 of Figure 10 or the amino acids No. 1 to 80 of Figure 10, and the amino acid sequence of the protein deduced from the nucleotide sequence coding for mouse BTC-GF is as that comprising the amino acids No. 1 to No. 146 of Figure 9.

    摘要翻译： 重组非糖基化哺乳动物生长因子（BTC-GF）刺激人平滑肌细胞的增殖。 特别地，从编码人BTC-GF的核苷酸序列推测的蛋白质的氨基酸序列是包含图10的氨基酸No.1至No.147或图10的氨基酸No.1至80， 并且从编码小鼠BTC-GF的核苷酸序列推测的蛋白质的氨基酸序列是包含图9的第1至第146号氨基酸的氨基酸序列。