专利检索 ap:("Targacept, Inc.") AND inv:"SHOWALTER, Todd" 第 1 页

1.

发明公开
DERIVATIVES OF OXABISPIDINE AS NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS 审中-公开
标题翻译： OXABISPIDIN作为配体为神经元烟碱型乙酰胆碱受体衍生物

公开(公告)号：EP2356125A1

公开(公告)日：2011-08-17

申请号：EP09774421.3

申请日：2009-07-01

申请人： Targacept, Inc.

发明人： MAZUROV, Anatoly , MIAO, Lan , XIAO, Yun-de , YOHANNES, Daniel , AKIREDDY, Srinivisa, Rao , BREINING, Scott, R. , KOMBO, David , MURTHY, V. Srinivasa , FEDOROV, Nikolai , SHOWALTER, Todd

IPC分类号： C07D498/04 , A61K31/5386 , A61P25/00

CPC分类号： C07D498/04

摘要： The present invention relates to compounds of formula (I) that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with d sfunction of the central nervous s stem (CNS).

2.

发明公开
1,4-DIAZABICYCLO[3.2.2]NONANES AS NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS 审中-公开
标题翻译： 1,4-DIAZABICYCLO- [3.2.2-] NONANE ALS NEURONALE NIKOTINACETYLCHOLINREZEPTORLIGANDEN

公开(公告)号：EP2748170A1

公开(公告)日：2014-07-02

申请号：EP12753884.1

申请日：2012-08-20

申请人： Targacept, Inc.

发明人： MAZUROV, Anatoly A. , MIAO, Lan , SHOWALTER, Todd

IPC分类号： C07D498/04 , A61K31/551 , A61P25/00

CPC分类号： C07D519/00 , A61K31/551 , C07D498/04

摘要： The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including inflammatory diseases and diseases associated with dysfunction of the central nervous system (CNS).

3.

发明公开
NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS 审中-公开
标题翻译： NICHTKOMPETITIVE ANTAGONISTEN DES NIKOTINREZEPTORS

公开(公告)号：EP2661421A2

公开(公告)日：2013-11-13

申请号：EP12731898.8

申请日：2012-01-05

申请人： Targacept, Inc.

发明人： AKIREDDY, Srinivasa Rao , BREINING, Scott R. , MELVIN, Matt S. , MURTHY, Srinivasa V. , MAZUROV, Anatoly A. , BHATTI, Balwinder Singh , STRACHAN, Jon-Paul , HEEMSTRA, Ronald Joseph , SHOWALTER, Todd , XIAO, Yunde , HAMMOND, Philip S. , MIAO, Lan , KOMBO, David , YOHANNES, Daniel , SPEAKE, Jason

IPC分类号： C07C211/35 , A61K31/13 , A61P9/12

CPC分类号： C07D493/08 , C07C211/38 , C07C2602/40 , C07C2602/42 , C07C2602/44

摘要： The present invention relates to compounds that modulate nicotinic receptors as non-competitive antagonists, methods for their synthesis, methods for their use, and their pharmaceutical compositions.

摘要翻译： 本发明涉及将烟碱受体调节为非竞争性拮抗剂的化合物，其合成方法，其使用方法及其药物组合物。