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公开(公告)号:EP2574188A1
公开(公告)日:2013-04-03
申请号:EP11783835.9
申请日:2011-05-19
申请人: Targacept, Inc. , AstraZeneca AB
发明人: DULL, Gary Maurice , GENUS, John , RATILAINEN, Tommi , RYBERG, Per Olof , HELLSTRÖM, Janna , WAHLSTRÖM, Niklas , WÄNNMAN, Thomas
IPC分类号: C07C29/40 , C07C211/21 , C07C231/14 , C07D213/65
CPC分类号: C07D213/65 , C07C29/36 , C07C211/21 , C07C269/04 , C07C33/03 , C07C271/12
摘要: An improved process for the preparation of aryl substituted olefinic amines such as (2S)-(4E)-N-methyl-5-[3-(5-isopropoxypyridin)yl]-4-penten-2-amine and (2S)-(4E)-N- methyl-5-[3-(5-methoxypyridin)yl]-4-penten-2-amine and new intermediates used in said process.