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公开(公告)号：EP4414707A1
公开(公告)日：2024-08-14
申请号：EP23156155.6
申请日：2023-02-10
发明人： VOGELE, Kilian , SIMMEL, Friedrich
IPC分类号： G01N33/553 , G01N33/569
CPC分类号： G01N33/56911 , G01N2800/4420130101 , G01N33/553 , G01N2333/0120130101
摘要： The invention relates to a method for determining binding of a tail fiber protein to a cell surface epitope of a bacterium using tail fiber protein-coated nanoparticles that undergo plasmonic coupling upon binding to the bacterial epitope. The invention further relates to the use of said nanoparticles for the method described above. Moreover, the invention relates to a method for determining promising bacteriophage candidates for antimicrobial treatment using said nanoparticles. The invention further relates to a kit for detecting plasmonic coupling.
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公开(公告)号：EP4407020A1
公开(公告)日：2024-07-31
申请号：EP23153442.1
申请日：2023-01-26
IPC分类号： C12M1/00
摘要： The invention relates to a chamber system for cell-free production of proteins of interest, comprising:
at least one reaction chamber (10), being configured to hold a reaction solution (12) and being configured to produce proteins of interest using the reaction solution (12);
at least one feeding chamber (20), being disposed adjacent to the at least one reaction chamber (10) and being configured to hold a feeding solution (22);
at least one semi-permeable membrane (30), connecting the at least one feeding chamber (20) with the at least one reaction chamber (10), wherein the semi-permeable membrane (30) is configured to allow diffusing at least part of the feeding solution (22) from the at least one feeding chamber (20) into the at least one reaction chamber (10);
wherein the at least one feeding chamber (20) comprises a feeding chamber access (21) that is configured to allow access to the feeding solution (22) in the at least one feeding chamber (20).-
公开(公告)号：EP4349982A1
公开(公告)日：2024-04-10
申请号：EP22199974.1
申请日：2022-10-06
摘要： The present invention relates to a method for in vitro provision of lysis deficient viruses, in particular lysis deficient bacteriophages, in a cell-free expression system. Further aspects of the invention relate to a correspondingly provided lysis deficient virus, in particular bacteriophage, and the use thereof.
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4.发明公开
公开(公告)号：EP4342538A1
公开(公告)日：2024-03-27
申请号：EP22196655.9
申请日：2022-09-20
摘要： The present invention relates to multi-peptide structures comprising at least one heterogenous functional site wherein the at least one heterogenous functional site is composed of at least two homologous peptides, which differ by at least one amino acid, a method for providing such multi-peptide structures, compositions comprising such multi-peptide structures as well as the use of such multi-peptide structures and compositions as an universal anti-microbial agent, in particular in medicine, chemistry, biotechnology, agriculture and/or food industry.
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公开(公告)号：EP3999631A1
公开(公告)日：2022-05-25
申请号：EP20739712.6
申请日：2020-07-16
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公开(公告)号：EP3999630A1
公开(公告)日：2022-05-25
申请号：EP20739418.0
申请日：2020-07-16
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