公开(公告)号：EP1841420B1

公开(公告)日：2011-12-07

申请号：EP06717284.1

申请日：2006-01-04

申请人： Temple University - Of The Commonwealth System of Higher Education

发明人： REDDY, M.V. Ramana ,  REDDY, E. Premkumar, ,  COSENZA, Stephen, C. ,  BAKER, Stacey, J.

IPC分类号： A01N41/10 ,  A01N43/06 ,  A01N43/08 ,  A61K31/10 ,  A61K31/34 ,  A61K31/38 ,  C07C315/00 ,  C07C317/00

CPC分类号： A61K31/337

摘要： α,β-Unsaturated sulfones, sulfoxides and sulfonamides according to Formula I: wherein Ar1, Ar2, X, n, * and R are as defined herein are useful for the treatment of proliferative disorders which are resistant to treatment by ATP-competitive kinase inhibitors.

公开(公告)号：EP1841420A2

公开(公告)日：2007-10-10

申请号：EP06717284.1

申请日：2006-01-04

申请人： Temple University of the Commonwealth System of Higher Education

发明人： REDDY, M.V. Ramana ,  REDDY, E. Premkumar, ,  COSENZA, Stephen, C. ,  BAKER, Stacey, J.

IPC分类号： A61K31/337

CPC分类号： A61K31/337

摘要： α,β-Unsaturated sulfones, sulfoxides and sulfonamides according to Formula I: wherein Ar1, Ar2, X, n, * and R are as defined herein are useful for the treatment of proliferative disorders which are resistant to treatment by ATP-competitive kinase inhibitors.