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    CONFIGURABLE METHODS AND SYSTEMS OF GROWING AND HARVESTING CELLS IN A HOLLOW FIBER BIOREACTOR SYSTEM
    1.
    发明公开
    CONFIGURABLE METHODS AND SYSTEMS OF GROWING AND HARVESTING CELLS IN A HOLLOW FIBER BIOREACTOR SYSTEM 审中-公开
    可配置方法和繁殖和收获细胞的系统，中空纤维生物反应器系统

    公开(公告)号：EP2625263A2

    公开(公告)日：2013-08-14

    申请号：EP11773364.2

    申请日：2011-10-07

    申请人： Terumo BCT, Inc.

    发明人： STANTON, Edward Allan IV ,  ANTWILER, Glen Delbert ,  HOWLEY, Patrick J. ,  KINZIE, Michael E. ,  DODD, Jon A. ,  MEDINA, Casey V.

    IPC分类号： C12M3/06 ,  G05B19/042

    摘要： Embodiments described herein generally relate to methods and systems for configuring settings of a cell expansion system including a bioreactor. Through a user interface, a user may configure display settings, system settings, and settings associated with protocols for loading, growing and/or harvesting cells. In configuring settings for protocols and associated processes, a diagram view or window of the cell expansion system is displayed in embodiments. The diagram view displays the process settings as graphical user interface elements. Settings available for configuration are enabled for selection in the diagram view. The diagram view allows the user to visualize the settings available for task configuration and to configure enabled settings. Configured settings are stored and capable of retrieval for subsequent execution or modification of the applicable protocol.

    摘要翻译： 在基因反弹描述的实施例涉及方法和用于定制协议用于与细胞扩增系统中使用的系统，通过用户接口，用户可以创建一个定制任务用于装载，生长和/或收获细胞。 自定义任务可以包含一个或多个步骤，其中用户可以添加或省略步骤，如期望的那样。 数据可被输入用于与自定义任务，其中的实施例提供用于搜索数据相关联的设置进行自定义任务每次输入。 在另一个实施方式为自定义任务的设置可以在其中搜索设置进行配置可以存储并在自定义任务的选择而检索。 一个自定义的任务的定制和配置可能会发生使用细胞扩增系统中，在该方法中设置与图形用户界面元素相关联的图视图。

    CONCENTRATING COMPONENTS OF FLUID CIRCULATED THROUGH A CELL GROWTH CHAMBER
    3.
    发明公开
    CONCENTRATING COMPONENTS OF FLUID CIRCULATED THROUGH A CELL GROWTH CHAMBER 审中-公开
    KONZENTRATION VON KOMPONENTEN EINER DURCH EINE ZELLWACHSTUMSKAMMER ZIRKULIERENDENFLÜSSIGKEIT

    公开(公告)号：EP2885392A1

    公开(公告)日：2015-06-24

    申请号：EP13756776.4

    申请日：2013-08-20

    申请人： Terumo BCT, Inc.

    发明人： NANKERVIS, Brian J. ,  DILORENZO, Thomas G. ,  KINZIE, Michael E. ,  JONES, Mark E.

    IPC分类号： C12M1/12 ,  C12M1/00 ,  B01D61/14

    CPC分类号： C12M47/02 ,  B01D61/14 ,  B01D61/22 ,  B01D63/02 ,  B01D2311/12 ,  C12M25/12 ,  C12M29/16

    摘要： One or more embodiments are described directed to a method and system for concentrating components of a fluid circulated through a cell growth chamber such as a cell growth chamber. Accordingly, embodiments include methods and systems that utilize a tangential flow filter to concentrate components of a fluid that in embodiments includes expanded cells. In embodiments, a concentrated fluid component and a concentrated cell component are generated by flowing the fluid with expanded cells across a tangential flow filter. The concentrated cell component may be recirculated to the tangential flow filter to reach some desired concentration of cells. The concentrated fluid component may be collected to utilize cellular-produced constituents in the concentrated fluid component.

    摘要翻译： 对一个或多个实施方案进行描述，涉及用于浓缩循环通过诸如细胞生长室的细胞生长室的流体的组分的方法和系统。 因此，实施方案包括使用切向流过滤器来浓缩流体的组分的方法和系统，其在实施方案中包括膨胀的细胞。 在实施方案中，通过使流体与膨胀的细胞流过切向流过滤器而产生浓缩的流体组分和浓缩的细胞组分。 浓缩的细胞组分可以再循环到切向流过滤器以达到一些所需的细胞浓度。 可以收集浓缩的流体组分以利用浓缩流体组分中的细胞产生的成分。

    METHODS AND SYSTEMS OF GROWING AND HARVESTING CELLS IN A HOLLOW FIBER BIOREACTOR SYSTEM WITH CONTROL CONDITIONS
    4.
    发明公开
    METHODS AND SYSTEMS OF GROWING AND HARVESTING CELLS IN A HOLLOW FIBER BIOREACTOR SYSTEM WITH CONTROL CONDITIONS 审中-公开
    方法和系统育种和收获小区在控制条件下的中空纤维生物反应器系统

    公开(公告)号：EP2625264A2

    公开(公告)日：2013-08-14

    申请号：EP11773366.7

    申请日：2011-10-07

    申请人： Terumo BCT, Inc.

    发明人： DILORENZO, Thomas G. ,  STANTON, Edward Allan IV ,  ANTWILER, Glen Delbert ,  KINZIE, Michael E. ,  NANKERVIS, Brian J. ,  GIVENS, Monique ,  MEDINA, Casey V. ,  DODD, Jon A.

    IPC分类号： C12M3/06

    CPC分类号： C12M41/44 ,  C12M23/42 ,  C12M23/44 ,  C12M25/10 ,  C12M25/12 ,  C12M29/16 ,  C12M29/20 ,  C12M41/48 ,  G06F8/38

    摘要： Embodiments described herein generally relate to methods and systems for configuring settings of a cell expansion system including a bioreactor. Through a user interface, a user may configure display settings, system settings, and settings associated with protocols for loading, growing and/or harvesting cells. In configuring settings for protocols and associated processes, a diagram view or window of the cell expansion system is displayed in embodiments. The diagram view displays the process settings as graphical user interface elements. Settings available for configuration are enabled for selection in the diagram view. The diagram view allows the user to visualize the settings available for task configuration and to configure enabled settings. Configured settings are stored and capable of retrieval for subsequent execution or modification of the applicable protocol.

    摘要翻译： 在基因反弹描述的实施例涉及方法和用于定制协议用于与细胞扩增系统中使用的系统，通过用户接口，用户可以创建一个定制任务用于装载，生长和/或收获细胞。 自定义任务可以包含一个或多个步骤，其中用户可以添加或省略步骤，如期望的那样。 数据可被输入用于与自定义任务，其中的实施例提供用于搜索数据相关联的设置进行自定义任务每次输入。 在另一个实施方式为自定义任务的设置可以在其中搜索设置进行配置可以存储并在自定义任务的选择而检索。 一个自定义的任务的定制和配置可能会发生使用细胞扩增系统中，在该方法中设置与图形用户界面元素相关联的图视图。