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公开(公告)号：EP2956137A1
公开(公告)日：2015-12-23
申请号：EP14751103.4
申请日：2014-02-13
发明人： TARCIC, Nora , BAR-ZOHAR, Dan , HAYARDENY, Liat , GILGUN SHERKI, Yossi , GORFINE, Tali , KNAPPERTZ, Volker , SORANI, Ella
IPC分类号： A61K31/47 , A61K31/197 , A61P25/00
CPC分类号： A61K31/4704
摘要： This invention provides a method for treating a human subject afflicted with a progressive form of multiple sclerosis, comprising periodically administering to the human subject an amount of laquinimod effective to treat the human subject. This invention also provides laquinimod for use in treating a human subject afflicted with a progressive form of multiple sclerosis. This invention further provides pharmaceutical compositions and packages comprising an effective amount of laquinimod for treating a progressive form of multiple sclerosis.
摘要翻译： 本发明提供了治疗患有进行性多发性硬化症的人类受试者的方法，包括定期向人类受试者施用有效治疗人类受试者的量的拉喹莫德。 本发明还提供了用于治疗患有进行性多发性硬化症的人类受试者的拉喹莫德。 本发明进一步提供了包含有效量的拉喹莫德用于治疗多发性硬化的进行性形式的药物组合物和包装。
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公开(公告)号：EP3094330A1
公开(公告)日：2016-11-23
申请号：EP15737558.5
申请日：2015-01-15
发明人： BROWN, Kurt, A. , SORANI, Ella
IPC分类号： A61K31/47 , A61K31/4704 , A61P37/02
CPC分类号： A61K31/4704 , A61K9/48
摘要： This invention provides a method of treating a subject suffering from Crohn's disease, comprising periodically administering to the subject an amount of laquinimod or pharmaceutically acceptable salt thereof effective to treat the subject, which amount of laquinimod is less than 0.5 mg/day, wherein the subject is naive to laquinimod and the administration continues for at least 12 weeks, or wherein the subject is being treated with another Crohn's disease therapy at baseline. Furthermore, this invention provides a corresponding therapeutic package, use of laquinimod or pharmaceutically acceptable salt thereof in the manufacture of a medicament, and pharmaceutical composition.
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