公开(公告)号：EP3697397A1

公开(公告)日：2020-08-26

申请号：EP17929165.3

申请日：2017-10-19

申请人： Texas State University ,  Universiteit Leiden

发明人： KORNIENKO, Alexander ,  BETANCOURT, Tania ,  BONNET, Sylvestre ,  VAN RIXEL, Vincent

IPC分类号： A61K31/00 ,  A61K31/28 ,  A61K31/555 ,  A61K33/24 ,  A61K41/00 ,  A61N5/06

公开(公告)号：EP2629781A1

公开(公告)日：2013-08-28

申请号：EP11784772.3

申请日：2011-10-18

申请人： Universiteit Leiden

发明人： BONNET, Sylvestre

IPC分类号： A61K33/24

CPC分类号： C07F15/0053 ,  A61K31/58 ,  A61K33/24 ,  A61K41/0042 ,  A61K45/06

摘要： Photosensitive compounds for use in a method of treating a disease or condition are described. The photosensitive compounds have the formula R-Y, wherein R is a ruthenium complex and Y is at least one sulphur-containing photoreleasable group, and the compounds comprise at least one ruthenium-sulphur bond; or a pharmaceutically acceptable salt, solvate, ester or amide, such that upon influence of visible or near infra-red light (400-1400nm) in vivo, said at least one ruthenium-sulphur bond is broken, thereby generating a pharmacologically active compound.