公开(公告)号：EP1898920A1

公开(公告)日：2008-03-19

申请号：EP06741586.9

申请日：2006-05-30

申请人： Thallion Pharmaceuticals Inc.

发明人： RANGER, Maxime ,  ROUX, Emmanuelle ,  HARVEY, Michael ,  WHITE, Gregory, L.

IPC分类号： A61K31/5513 ,  A61P35/00

CPC分类号： A61K31/5513 ,  A61K31/551 ,  A61K31/675

摘要： The invention relates to pharmaceutical formulations comprising a farnesyl dibenzodiazepinone compound, or an analog, or a pharmaceutically acceptable salt or prodrug thereof, and a pharmaceutically acceptable surfactant and having improved chemical and biological properties. Such a formulation is a ready-to-use solution suitable for parenteral or non-parenteral administration or a bulk formulation for ex tempore preparation. The present invention also relates to therapeutic methods using the formulations, and methods for their preparation.

公开(公告)号：EP1983997A2

公开(公告)日：2008-10-29

申请号：EP07762857.6

申请日：2007-01-26

申请人： Thallion Pharmaceuticals Inc.

发明人： MORRIS, Patrick ,  YEBOAH, Faustinus ,  MCALPINE, James ,  RANGER, Maxime ,  ROUX, Emmanuelle ,  HARVEY, Michael

IPC分类号： A61K31/551 ,  C07D243/10

CPC分类号： C07D243/38

摘要： The present invention relates to crystalline forms of ECO-4601 and the processes for providing them. The invention further relates to pharmaceutical compositions comprising the crystalline forms and to methods of use of the crystalline forms as pharmaceuticals.

摘要翻译： 本发明涉及ECO-4601的结晶形式和提供它们的方法。 本发明进一步涉及包含晶型的药物组合物以及使用该晶型作为药物的方法。