专利检索 ap:("The Board of Trustees of The Leland S. Stanford Junior University") AND inv:"KHOSLA, Chaitan" 第 1 页

1.

发明公开
BIOSYNTHESIS OF POLYKETIDE SYNTHASE SUBSTRATES 无效
标题翻译：聚酮化合物合酶底物的生物合成

公开(公告)号：EP1222304A2

公开(公告)日：2002-07-17

申请号：EP00972196.0

申请日：2000-10-13

申请人： The Board of Trustees of The Leland S. Stanford Junior University

发明人： KHOSLA, Chaitan , PFEIFER, Blaine

IPC分类号： C12P11/00 , C12P19/62 , C12N1/21

CPC分类号： C12N1/20 , C12P11/00 , C12P19/62

摘要： The use of enzymes which catalyze the production of starter and extender units for polyketides is described. These enzymes may be used to enhance the yield of polyketides that are natively produced or polyketides that are rationally designed. By using these techniques, the synthesis of a complete polyketide has been achieved in E. coli. This achievement permits a host organism with desirable characteristics to be used in the production of such polyketides and to assess the results of gene shuffling.