专利检索 ap:("The Government of the United States of America as represented by the Secretary of the Department of Health AND Human Services") AND inv:"THOMAS, Craig, J." 第 1 页

1.

发明授权
LOW MOLECULAR WEIGHT THYROID STIMULATING HORMONE RECEPTOR (TSHR) AGONISTS 有权
标题翻译：促甲状腺激素（TSH）受体激动剂ERINGEM分子量

公开(公告)号：EP2358684B1

公开(公告)日：2014-08-06

申请号：EP08876356.0

申请日：2008-10-20

申请人： The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services

发明人： GERSHENGORN, Marvin, C. , NEUMANN, Susanne , RAAKA, Bruce, M. , THOMAS, Craig, J. , INGLESE, James , SOUTHALL, Noel, T. , TITUS, Steven , ZHENG, Wei , HUANG, Wenwei , KRAUSE, Gerd , KLEINAU, Gunnar

IPC分类号： C07D401/06 , C07D405/06 , C07D239/91 , C07D487/04

CPC分类号： C07D405/06 , A61K31/517 , A61K49/0004 , A61K51/00 , C07D239/91 , C07D401/06 , C07D405/14 , C07D487/04

2.

发明授权
LOW MOLECULAR WEIGHT THYROID STIMULATING HORMONE RECEPTOR (TSHR) AGONISTS 有权
标题翻译：低分子量甲状腺激素受体激动剂（TSHR）激动剂

公开(公告)号：EP2358684B8

公开(公告)日：2014-10-22

申请号：EP08876356.0

申请日：2008-10-20

申请人： The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services , Forschungsverbund Berlin e.V.

发明人： GERSHENGORN, Marvin, C. , NEUMANN, Susanne , RAAKA, Bruce, M. , THOMAS, Craig, J. , INGLESE, James , SOUTHALL, Noel, T. , TITUS, Steven , ZHENG, Wei , HUANG, Wenwei , KRAUSE, Gerd , KLEINAU, Gunnar

IPC分类号： C07D401/06 , C07D405/06 , C07D239/91 , C07D487/04

CPC分类号： C07D405/06 , A61K31/517 , A61K49/0004 , A61K51/00 , C07D239/91 , C07D401/06 , C07D405/14 , C07D487/04

3.

发明公开
LOW MOLECULAR WEIGHT THYROID STIMULATING HORMONE RECEPTOR (TSHR) AGONISTS 有权
标题翻译：促甲状腺激素（TSH）受体激动剂ERINGEM分子量

公开(公告)号：EP2358684A1

公开(公告)日：2011-08-24

申请号：EP08876356.0

申请日：2008-10-20

申请人： The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services

发明人： GERSHENGORN, Marvin, C. , NEUMANN, Susanne , RAAKA, Bruce, M. , THOMAS, Craig, J. , INGLESE, James , SOUTHALL, Noel, T. , TITUS, Steven , ZHENG, Wei , HUANG, Wenwei , KRAUSE, Gerd , KLEINAU, Gunnar

IPC分类号： C07D235/18 , A61K31/4184

CPC分类号： C07D405/06 , A61K31/517 , A61K49/0004 , A61K51/00 , C07D239/91 , C07D401/06 , C07D405/14 , C07D487/04

摘要： Disclosed are oxo-hydroquinazolines that are useful as selective TSHR agonists. The compounds may be used for detecting or treating thyroid cancer, or treating a bone degenerative disorder.