-
1.发明授权DICHLOROACETATE IN COMBINATION WITH AN INOTROPE FOR CARDIOPROTECTION 有权DICHLOROAZETAT连同药物性肌力CARDIO保护
公开(公告)号：EP1708692B1
公开(公告)日：2010-07-07
申请号：EP04702767.7
申请日：2004-01-16
CPC分类号： A61K31/19 , Y02A50/411 , A61K2300/00
摘要： The present invention provides composition and methods for maintaining cardiac function by administering dichloroacetate (DCA) in combination with an inotrope.
-
公开(公告)号：EP1868982A2
公开(公告)日：2007-12-26
申请号：EP06765523.3
申请日：2006-02-23
IPC分类号： C07C69/74 , A61K31/21 , A61K31/185 , A61K31/34 , C07C321/22 , C07C323/51 , C07C327/24 , C07D307/54
CPC分类号： C07C69/757 , C07C69/74 , C07C69/743 , C07C69/753 , C07C219/12 , C07C233/60 , C07C233/63 , C07C327/30 , C07C327/32 , C07C2601/02 , C07C2601/04 , C07D277/24 , C07D295/088 , C07D307/38 , C07D319/06 , C07D319/12
摘要： The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells: Formula (I) wherein W, Cyc, p, Y, X, Z, R, R1, R2, R3, R4, I, m and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia.
-
公开(公告)号：EP1499580B1
公开(公告)日：2012-03-28
申请号：EP03745384.2
申请日：2003-03-31
IPC分类号： C07C69/757 , C07C233/63 , C07C217/08 , A61K31/215 , A61K31/164 , A61K31/13 , A61P3/08
CPC分类号： C07C69/74 , C07C69/753 , C07C217/08 , C07C219/12 , C07C233/60 , C07C233/63 , C07C2601/02 , C07C2601/04
摘要： The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells wherein W, Cyc, p, , X, Z, R, K-, R, R1, R2, R3,R4, I and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose Oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia.
-
4.发明公开DICHLOROACETATE IN COMBINATION WITH AN INOTROPE FOR CARDIOPROTECTION 有权DICHLOROAZETAT连同药物性肌力CARDIO保护
公开(公告)号：EP1708692A1
公开(公告)日：2006-10-11
申请号：EP04702767.7
申请日：2004-01-16
CPC分类号： A61K31/19 , Y02A50/411 , A61K2300/00
摘要： The present invention provides composition and methods for maintaining cardiac function by administering dichloroacetate (DCA) in combination with an inotrope.
-
5.发明授权COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE 有权VERBINDUNGEN ZUR刺激VON GLUCOSE-VERBRAUCH UND VERWENDUNGSVERFAHRENDAFÜR
公开(公告)号：EP1868982B1
公开(公告)日：2015-04-29
申请号：EP06765523.3
申请日：2006-02-23
IPC分类号： C07C69/74 , C07C69/743 , C07C69/753 , C07C69/757 , C07C219/12 , C07C233/60 , C07C233/63 , C07C327/30 , C07C327/32 , C07D277/24 , C07D307/38 , C07D319/06 , C07D319/12 , C07D295/088 , C07H13/08 , A61K31/215 , A61K31/25 , A61K31/16 , A61K31/33 , A61K31/7024 , A61P9/10
CPC分类号： C07C69/757 , C07C69/74 , C07C69/743 , C07C69/753 , C07C219/12 , C07C233/60 , C07C233/63 , C07C327/30 , C07C327/32 , C07C2601/02 , C07C2601/04 , C07D277/24 , C07D295/088 , C07D307/38 , C07D319/06 , C07D319/12
-
-
-
-
搜索结果
5 条记录 (耗时 0.015 秒)
