专利检索 ap:("The Johns Hopkins University") AND inv:"SHIM, Joong, Sup" 第 1 页

1.

发明授权
QUINOLINE COMPOUNDS AS INHIBITORS OF ANGIOGENESIS, HUMAN METHIONINE AMINOPEPTIDASE, AND SIRT1, AND METHODS OF TREATING DISORDERS 有权
标题翻译：喹啉化合物作为血管生成抑制剂，人蛋氨酸氨肽酶和SIRT1，以及治疗疾病的方法

公开(公告)号：EP2350012B1

公开(公告)日：2017-06-28

申请号：EP09819542.3

申请日：2009-10-06

申请人： The Johns Hopkins University

发明人： LIU, Jun, O. , SHIM, Joong, Sup , CHONG, Curtis, R. , BHAT, Shridhar

IPC分类号： C07D215/28 , C07D215/04 , A61K31/47 , A61P35/00 , C07D417/14

CPC分类号： C07D215/04 , A61K31/47 , C07D417/14 , Y02A50/401

摘要： Described herein are methods of inhibiting methionine aminopeptidase or SirT1, inhibiting angiogenesis, and treating disorders (or symptoms thereof) associated with methionine aminopeptidase, SirT1 and/or angiogenesis, wherein a compound of the invention is administered to a subject.

摘要翻译： 本文描述了抑制甲硫氨酸氨肽酶或SirT1，抑制血管生成和治疗与甲硫氨酸氨肽酶，SirT1和/或血管生成相关的病症（或其症状）的方法，其中将本发明的化合物施用于受试者。

2.

发明公开
QUINOLINE COMPOUNDS AS INHIBITORS OF ANGIOGENESIS, HUMAN METHIONINE AMINOPEPTIDASE, AND SIRT1, AND METHODS OF TREATING DISORDERS 有权
标题翻译：喹啉ALS血管生成，人道和METHIONINAMINOPEPTIDASE- SIRT1抑制剂AND METHOD FOR疾病治疗

公开(公告)号：EP2350012A2

公开(公告)日：2011-08-03

申请号：EP09819542.3

申请日：2009-10-06

申请人： The Johns Hopkins University

发明人： LIU, Jun, O. , SHIM, Joong, Sup , CHONG, Curtis, R. , BHAT, Shridhar

IPC分类号： C07D215/28 , C07D215/04 , A61K31/47 , A61P35/00

CPC分类号： C07D215/04 , A61K31/47 , C07D417/14 , Y02A50/401

摘要： Described herein are methods of inhibiting methionine aminopeptidase or SirT1, inhibiting angiogenesis, and treating disorders (or symptoms thereof) associated with methionine aminopeptidase, SirT1 and/or angiogenesis, wherein a compound of the invention is administered to a subject.