专利检索 ap:("The Provost, Fellows, Foundation Scholars, & the other members of Board, of the College of the Holy & Undiv. Trinity of Queen Elizabeth near Dublin" OR "The Coombe Lying-in Hospital") AND inv:"DALY, Sean" 第 1 页

1.

发明授权
COMPOSITION AND METHOD FOR TREATMENT OF PRETERM LABOR 有权
标题翻译： ZUSAMMENSETZUNG UND VERFAHREN ZUR BEHANDLUNG VON VORZEITIGEN WEHEN

公开(公告)号：EP2334300B1

公开(公告)日：2016-02-17

申请号：EP09783381.8

申请日：2009-09-24

申请人： The Provost, Fellows, Foundation Scholars, & the other members of Board, of the College of the Holy & Undiv. Trinity of Queen Elizabeth near Dublin , The Coombe Lying-in Hospital

发明人： O'NEILL, Luke Anthony , O'LEARY, John , DALY, Sean , SCHARFE NUGENT, Andrea

IPC分类号： A61K31/47 , A61K38/17 , A61P29/00

CPC分类号： A61K31/47 , A61K31/00 , A61K31/7088 , A61K38/177 , A61K45/06 , C12N15/117 , C12N2310/17 , A61K2300/00

2.

发明公开
COMPOSITION AND METHOD FOR TREATMENT OF PRETERM LABOR 有权
标题翻译：组合物及法治疗早产

公开(公告)号：EP2334300A2

公开(公告)日：2011-06-22

申请号：EP09783381.8

申请日：2009-09-24

申请人： The Provost, Fellows and Scholars of the College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin , The Coombe Lying-in Hospital

发明人： O'NEILL, Luke Anthony , O'LEARY, John , DALY, Sean , SCHARFE NUGENT, Andrea

IPC分类号： A61K31/47 , A61K38/17 , A61P29/00

CPC分类号： A61K31/47 , A61K31/00 , A61K31/7088 , A61K38/177 , A61K45/06 , C12N15/117 , C12N2310/17 , A61K2300/00

摘要： The invention provides a method for treating or preventing preterm labor in pregnant female subjects. The method comprises the step of administering a therapeutically effective amount of a Toll-like Receptor 9 antagonist sufficient to prevent the activation of Toll-like Receptor 9 by fetal DNA. The invention further provides compositions comprising a Toll-like Receptor 9 antagonist for use in the methods of the invention. Said compositions and methods enhance gestation and therefore improve neonatal morbidity and mortality.